Alopecia Areata Incognita in Cronkhite-Canada Syndrome
December 2016
in “
British Journal of Dermatology
”
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Studysummary This report presents evidence that alopecia areata incognita may be a possible mechanism of hair loss in patients with Cronkhite–Canada syndrome.
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The case report described a 49-year-old Chinese woman with Cronkhite-Canada syndrome who experienced rapid and extensive hair loss, gastrointestinal symptoms, and nail changes. A scalp biopsy indicated a possible mechanism of hair loss as alopecia areata incognita, characterized by a 'shift out of anagen' and increased telogen hair follicles with peri-bulbar lymphoid cell infiltrate. Treatment with prednisolone and mesalazine resulted in symptom improvement and hair and nail regrowth. This study suggested alopecia areata incognita as a potential cause of hair loss in Cronkhite-Canada syndrome, evidenced by the patient's response to treatment and biopsy results.
