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390-420 / 1000+ resultsresearch Dermatologic Changes in Experimental Model of Long COVID
This study suggests that the synthetic peptide SPIKENET (SPK) may protect against long-term skin alterations in mice following coronavirus infection, offering potential therapeutic intervention for similar effects in humans post-COVID-19.
research The effects of intradermal injections of spermidine on the growth rate of fibres and mitosis of wool follicles in Merino lambs
This study found that intradermal spermidine injections stimulated cell proliferation and increased fibre length growth rate in wool follicles of Merino lambs, without significantly affecting fibre diameter.
research Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase
This study found that overexpression of an enzyme in transgenic mice led to distorted polyamine levels, resulting in permanent hair loss and female infertility.
research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by interacting with SIRT1 and PARP1, highlighting a potential mechanism for addressing aging-related diseases.
research IV Międzynarodowe Sympozjum Studenckich Kół Naukowych Środowisko – Roślina – Zwierzę – Produkt Streszczenia
Custom skincare can be made based on genes, fewer cats in Lublin have FeLV/FIV than national average, and studies also looked at small water bodies, river pollution, guppy growth, toxins in biochars, palm oil issues, and pumpkin seed oil for hair strength.
research Characterization of Human Keratin-Associated Protein 1 Family Members
This study found that genes in the human keratin-associated protein 1 family may have evolved mainly through gene duplication of cysteine-repeat motifs.
research [Frizzy hair pathology].
This review discusses complications of frizzy hair syndrome and emphasizes the importance of precautionary measures, but it reports no new research findings.
research Male pattern hair loss - rh79g
research 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes
In this study, researchers found that the loss of SETDB1 in epidermal keratinocytes led to altered chromatin states, increased ERV expression, and activation of immune responses, while inhibiting these effects with certain antiviral drugs reduced skin inflammation and hair loss in a mouse model.
research Synchronous fluorescence as a green and selective method for the simultaneous determination of finasteride and tadalafil in dosage form and spiked human plasma
This study developed a synchronized fluorescence spectroscopic approach to quantify finasteride and tadalafil in various forms, achieving high accuracy with %recoveries of about 99.62% and 100.19% respectively, and demonstrated superior environmental friendliness compared to previous methods.
research PSS20 MEDIATION MODELING AND MEASUREMENT CHARACTERISTICS OF THE ITCH SEVERITY SCORE FROM A PHASE 2B TRIAL OF ORAL CP-690-550 IN PATIENTS WITH MODERATE TO-SEVERE PLAQUE PSORIASIS
This study found that the oral Janus kinase inhibitor CP-690,550 has a direct effect on reducing pruritus in patients with psoriasis, independent of clinician-assessed improvements in psoriasis severity.
research The hair growth promoting effects of ADSC
research DYS459, DYS391, DYS388 and DYS19 genetic loci have high allelic frequency in patients with prostate cancer
This study found that specific Y-chromosome alleles may influence susceptibility to prostate cancer in Iraqi males, suggesting their potential use in screening for the disease.
research Arabidopsis retromer subunit AtVPS29 is involved in SLY1-mediated gibberellin signaling
This study found that the retromer protein AtVPS29 in Arabidopsis plants modulates gibberellin signaling by upregulating the SLY1 protein and downregulating the RGA protein, ultimately enhancing the development of the root meristematic zone.
research 0953 Double knockdown of DKK1 and SFRP1, two key players in androgenetic alopecia, does not accelerate the hair-growth promoting effect of individual SFRP1 knockdown in healthy human hair follicles ex vivo
research Precocious Puberty
This article discusses diagnostic evaluations and management strategies for isosexual precocious puberty, emphasizing the importance of accurate identification and appropriate treatment, but it provides no new clinical findings.
research LncRNA018392 promotes the proliferation of Liaoning cashmere goat skin fibroblasts by upregulating CSF1R through binding to SPI1
This study found that the lncRNA018392, responsive to melatonin, accelerates cell proliferation in cashmere goats by recruiting the transcription factor SPI1 to upregulate the nearby gene CSF1R, which may explain the molecular mechanisms of cashmere growth.
research 446 Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway
In this study, finasteride was found to significantly reduce DHT levels and affect spermatogenic markers in rats, while DA-9401 co-treatment indicated potential ameliorative effects.
research Genome-Wide Association Study and Transcriptome Differential Expression Analysis of the Feather Rate in Shouguang Chickens
In this study, the researchers identified the SPEF2 and PRLR genes as potential candidates associated with feather rate phenotypes in Shouguang chickens through combined genome-wide association and differential expression analyses.
research SKUTECZNOŚĆ STOSOWANIA STANDARDOWYCH PROTOKOŁÓW KONTROLOWANEJ STYMULACJI JAJNIKÓW ZE SKŁADNIKIEM LH I BEZ NIEGO U PACJENTEK Z OBNIŻONĄ REZERWĄ JAJNIKOWĄ
This study found that using a combined LH and FSH stimulation protocol significantly increased clinical pregnancy rates in women with low ovarian reserve compared to the standard protocol.
research 189 Integrating single-cell and spatial transcriptomics of human hair follicles to define transcriptional signature of follicular dermal papilla
This study used single-cell and spatial transcriptomic profiling to identify specific molecular markers in human follicular dermal papilla cells, enhancing understanding of their role in hair follicle development.
research A Case of Trichorhinophalangeal Syndrome Caused by a Novel Heterozygous Nonsense Mutation in the TRPS1 Gene
In this case report, a 17-year-old male with a specific TRPS1 gene mutation presented with sparse, soft hair, short thumbs and toes, misaligned teeth, and distinctive bone abnormalities in the fingers and toes as observed through X-ray analysis.
research Faculty Opinions recommendation of The Venus flytrap trigger hair-specific potassium channel KDM1 can reestablish the K+ gradient required for hapto-electric signaling.
The KDM1 gene helps Venus flytraps close by managing potassium ions.
research Wheat Sprout Extract Stimulates Cell Proliferation via Phosphorylation of ERK and Akt in Human Dermal Papilla Cells
This study found that Wheat Sprout MeOH extract increased cell proliferation in human hair dermal papilla cells through the activation of ERK and Akt signaling pathways.
research An eruption of numerous spiny papules in a pediatric transplant patient
This article discusses a journal-based CME activity on rare viral skin eruptions in pediatric transplant patients and reports no new clinical results; it aims to improve physicians' knowledge and treatment of this condition.