research Prophylaxis of Recurring Low-Flow Priapism: Experimental Botulinum Neurotoxin Injection into the Ischiocavernosus Muscle
Botulinum neurotoxin injections into the pelvic muscles successfully prevented priapism relapse for over six months.
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research Comparison of Comedolytic Effect of Benzoyl Peroxide and Adapalene in Rhino Mice
Benzoyl peroxide and adapalene gels work differently to reduce acne in mice.
research British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012
Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.
research Alopecia Areata: Treatment Options and Efficacy
Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.
research Safety of Dermatologic Medications in Pregnancy and Lactation
Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.
research Alopecia Areata: A Comprehensive Review of Pathogenesis and Management
New treatments for Alopecia Areata show promise but need to be more effective and affordable.
research Male Accessory Sex Glands
Male accessory sex glands in rats rarely develop tumors and respond to hormones.
research Alopecia Areata: An Update
The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
research Stress and Aging: Effects of Disturbed Calcium Metabolism on Aging in a Progeria-Like Syndrome Induced by Dihydrotachysterol in Rats
Anabolic steroids may help prevent aging effects by reducing toxicity, not by their usual functions.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Vitiligo as a Reaction to Topical Treatment with Diphencyprone
Diphencyprone treatment for alopecia areata can cause vitiligo in some patients.
research Topical Treatment of Alopecia Areata
DNCB helps regrow hair in alopecia areata patients, but safer alternatives are needed.
research Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia
Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
research A Practical Approach to the Diagnosis and Management of Hair Loss in Children and Adolescents
Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.
research Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
research Diagnosing and Treating Hair Loss
The review suggests seeing a dermatologist for scarring hair loss and using treatments like minoxidil or finasteride for common male and female pattern hair loss.
research Hair Follicle Stem Cell Replication Stress Drives IFI16/STING-Dependent Inflammation in Hidradenitis Suppurativa
Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
research Sexuality in Premature Ovarian Insufficiency
Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
research Skin-Specific Expression of a Truncated E1a Oncoprotein Binding to p105-Rb Leads to Abnormal Hair Follicle Maturation Without Increased Epidermal Proliferation
In this study, researchers investigated the effects of a mutant Adenovirus E1a oncoprotein, NTdl646, on keratinocyte growth and differentiation in transgenic mice. The protein was expressed specifically in the skin using a keratin 5 promoter, resulting in two lines of mice with abnormal hair phenotypes, including short, crooked hair shafts and dystrophic or absent inner root sheaths. Despite these hair follicle maturation disturbances, the interfollicular epidermis remained normal, and there was no increase in spontaneous or chemically induced skin tumors. The study concluded that while the transgene disrupted keratinocyte maturation, it did not lead to increased epidermal proliferation or neoplastic growth.
research Frontal Fibrosing Alopecia: To Treat or Not to Treat?
Treatments for Frontal Fibrosing Alopecia have not been proven effective.
research Managing Polycystic Ovary Syndrome: A Cognitive Behavioral Strategy
Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.
research Immune Cell Regulation of the Hair Cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Neurosteroid-Sensitive δ-GABAA Receptors: A Role in Epileptogenesis?
Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.
research Follicular Mucinosis (Alopecia Mucinosa)
Systemic corticosteroids may effectively treat follicular mucinosis.
research 3D Printing of Skin Equivalents with Hair Follicle Structures and Epidermal-Papillary-Dermal Layers Using Gelatin/Hyaluronic Acid Hydrogels
Scientists created a 3D printed skin that includes hair and layers similar to real skin using a special gel.
research The Transient Role of Calcium and Vitamin D During the Developmental Hair Follicle Cycle
Vitamin D and calcium are essential for normal hair growth.
research Physical Inactivity Is a Disease Synonymous With a Non-Permissive Brain Disorder
Physical inactivity is a primary cause of many human illnesses.
research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.