13 citations,
February 2022 in “JAMA Dermatology” Spironolactone does not increase cancer risk and may lower prostate cancer risk, but more research is needed.
12 citations,
December 2002 in “Fertility and Sterility” Spironolactone plus finasteride works better for treating hirsutism.
12 citations,
January 1987 in “PubMed” Low-dose spironolactone is safe and effective for treating hirsutism.
11 citations,
October 2019 in “Cancers” Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
11 citations,
July 2019 in “The Journal of Sexual Medicine” Spironolactone might cause painful intercourse and decreased sexual arousal in women.
10 citations,
May 2020 in “Journal of The American Academy of Dermatology” Taking spironolactone doesn't increase the chance of breast cancer coming back.
10 citations,
September 2015 in “Gynecological Endocrinology” Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.
9 citations,
June 2020 in “Trials” The trial aims to test if spironolactone is an effective acne treatment for women without the side effects of current treatments.
9 citations,
November 2018 in “Acta Clinica Belgica” Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
8 citations,
August 2021 in “PubMed” Oral spironolactone effectively treats hair loss with mild, manageable side effects.
8 citations,
August 2020 in “Clinical and Experimental Dermatology” Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
8 citations,
April 1988 in “Journal of endocrinological investigation” Topical spironolactone cream doesn't cause hormone-related side effects in the body.
7 citations,
January 1990 Spironolactone improved hair density and quality in women with hair loss.
6 citations,
April 2013 in “Journal of Investigative Dermatology” Spironolactone might lower the chance of getting rosacea.
6 citations,
November 1993 in “Contact dermatitis” Spironolactone in anti-acne cream can cause allergic skin reactions in some people.
6 citations,
January 1984 in “PubMed” Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
5 citations,
December 2020 in “Journal of The American Academy of Dermatology” Minoxidil and spironolactone improve hair density and reduce shedding in girls.
4 citations,
January 2022 in “Dermatologic Therapy” Spironolactone is useful for treating acne and other skin conditions like excessive hair growth and certain types of hair loss.
4 citations,
December 2021 in “Journal of The American Academy of Dermatology” Doctors are prescribing spironolactone more often to treat acne and skin conditions in teenagers, and it seems safe and well-tolerated.
4 citations,
November 1996 in “European journal of endocrinology” Spironolactone may help treat excessive hair growth in girls, but more research is needed.
3 citations,
August 2019 in “Journal of The American Academy of Dermatology” Higher doses of spironolactone may improve acne in PCOS patients, but side effects are a concern.
3 citations,
July 1990 in “Acta dermato-venereologica” A man's baldness improved possibly due to a medication that blocks male hormones.
2 citations,
September 2023 in “Curēus” Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
2 citations,
July 2022 in “Frontiers in Medicine” Combining minoxidil with microneedling or spironolactone is more effective for female hair loss than using minoxidil alone.
2 citations,
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Topical spironolactone effectively treats hair loss in women.
2 citations,
January 1986 in “PubMed” Spironolactone improved symptoms in women with hormonal imbalances and had few side effects.
1 citations,
November 2023 in “Brain and behavior” Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.
1 citations,
June 2023 in “Cureus” Spironolactone may help improve symptoms and tear quality in dry eye disease.
1 citations,
August 2022 in “Journal of Cosmetic Dermatology” Using both 5% spironolactone and 5% minoxidil together is safe and more effective for treating hair loss.
1 citations,
November 2020 in “Journal of The American Academy of Dermatology” GSK-36 downregulation with UTMD improves plaque stability in atherosclerosis treatment.