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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

Best hair growth results from combining finasteride and minoxidil.

Paternal drug exposure can harm fertility, pregnancy outcomes, and offspring health, with specific drugs linked to various reproductive issues.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Understanding Polycystic Ovary Syndrome (PCOS) and its causes can lead to effective treatments.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

Uterine transplants for transgender women are feasible but need more research.

Women with PCOS and higher BMI, especially those with morbid obesity, are at greater risk for depression.

Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.