Clinical Management of Youth with Gender Dysphoria in Vancouver

    December 2013 in “ The Journal of Pediatrics ”
    Karine Khatchadourian, Shazhan Amed, Daniel L. Metzger
    Image of study
    TLDR Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
    The retrospective chart review of 84 youth with gender dysphoria treated at BC Children's Hospital between 1998 and 2011 found that cross-sex hormones were prescribed to 75% of patients, with a median age at initiation of 17.3 years for FtM and 17.9 years for MtF individuals. Gonadotropin-releasing hormone analog (GnRHa) treatment was given to 32% of patients. Minor complications from testosterone treatment in FtM patients included severe acne, androgenic alopecia, dyslipidemia, and mood swings, but no severe complications were reported with either testosterone or estrogen treatment. Three FtM patients temporarily stopped hormone treatment due to psychiatric issues or distress over androgenic alopecia. The study noted a decrease in suicide attempts from 12% to 5% after clinic visits and suggested that early treatment with puberty blockers or cross-sex hormones could alleviate emotional problems and suicidality in transgender youth. However, it emphasized the need for long-term follow-up studies to assess the safety of these treatments.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 154 results

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 8 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Discussion on Finasteride and life.

      in Chat  162 upvotes 1 month ago
      Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

      community 11 month progress on a cocktail regiment

      in Progress Pictures  440 upvotes 1 year ago
      The user "Dismal_Library_2264" shared their 11-month progress on a hair loss treatment regimen. They used dutasteride, topical minoxidil, dermarolling, a hair serum, and specific shampoos. They experienced some side effects but were overall satisfied with the results.

    Related Research

    2 / 2 results