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GlossaryGonadotropin-Releasing Hormone Agonists (GnRHa)

medications that initially boost, then suppress, sex hormone production

Gonadotropin-Releasing Hormone Agonists (GnRH agonists) are medications that mimic the natural hormone GnRH, which regulates the release of other hormones like luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Initially, they increase the production of these hormones, but with continuous use, they suppress their release, leading to reduced levels of sex hormones such as testosterone and estrogen. This makes them useful in treating hormone-sensitive conditions like prostate cancer, endometriosis, and certain types of breast cancer.

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Gonadotrophin-Releasing Hormone Agonist Therapy for Hirsutism Is as Effective as High Dose Cyproterone Acetate but Results in a Longer Remission

research Gonadotrophin-Releasing Hormone Agonist Therapy for Hirsutism Is as Effective as High Dose Cyproterone Acetate but Results in a Longer Remission

49 citations , April 1997 in “Human reproduction”

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

research Ovarian Hyperthecosis Coexisting with an Incidental Adrenal Lesion: Challenges in the Diagnostic Approach

May 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.

research Clinical and Hormonal Effects of Chronic Gonadotropin-Releasing Hormone Agonist Treatment in Polycystic Ovarian Disease

96 citations , October 1987 in “The Journal of Clinical Endocrinology & Metabolism”

Chronic GnRHa treatment can help manage endometrial hyperplasia and reduce ovarian androgen excess in PCO patients.

research Clinical Management of Youth with Gender Dysphoria in Vancouver

116 citations , December 2013 in “The Journal of Pediatrics”

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria

research Physical Changes, Laboratory Parameters, and Bone Mineral Density During Testosterone Treatment in Adolescents with Gender Dysphoria

71 citations , August 2019 in “The journal of sexual medicine”

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

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community Hey med experts explain this please??

in Research/Science 6 upvotes 2 months ago

Finasteride, dutasteride, saw palmetto, caffeine, spironolactone, acetyltetrapeptides, tea tree oil, hydrocortisone, zinc pyrithione, latanoprost, melatonin, marine protein supplements, PRP, microneedling, and valproate are discussed as treatments for hair loss. DHT reduction and inflammation control are key strategies.

community Is RU558841 actually related to heart issues?

in Finasteride/Dutasteride 11 upvotes 9 months ago

RU58841 may cause heart-related side effects like palpitations and chest pain, though evidence is mostly anecdotal. Users report mixed experiences, with some stopping due to side effects and others using it without issues, but concerns about its safety and sourcing remain.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 128 upvotes 2 years ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community 4 months after adding topical finasteride + melatonin, and switching from dermaroller to dr. Pen

in Treatment 224 upvotes 3 years ago

A user's experience using topical finasteride and melatonin to regrow hair, as well as their use of dermaroller versus dr. Pen for microneedling. People discussed the benefits of oral minoxidil and questioned if melatonin could help with hair regrowth.

community Guaranteed Way to Revive ALL Follicles. Transition, and then Transition Back & Maintain (for Men)

in Satire 250 upvotes 7 months ago

Transitioning genders humorously suggested for hair regrowth, noting some transgender individuals experience this. Discusses treatments like minoxidil, finasteride, and hormone therapy, but advises against transitioning solely for hair regrowth.

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