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The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Not enough vitamin B6 in pregnant rats' diets caused poor development and health in their babies.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride side effects in young men may be linked to specific gene variations.

Zinc made mice's coarse hair turn into fine hair without affecting skin structure.

Oxidative stress may contribute to hair loss in alopecia areata and antioxidants could potentially help as a treatment.

Low zinc levels may be linked to the return of gynecologic cancers.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Saw palmetto can help with prostate issues and may promote hair growth.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

Oestrogens are key for bone growth during puberty in both boys and girls.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.