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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

Oregano extract helps fix testis and sperm damage caused by finasteride.

Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Seminal bacteria can lower sperm quality in subfertile men.

A thorough initial check-up is essential before sperm banking to ensure the best chance of preserving good quality sperm.

Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Men with severe hair loss may have poorer sperm quality.

Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Some common medications can harm male fertility, but many effects can be reversed.

Finasteride may cause male infertility, stopping it can help.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

COVID-19 may harm male fertility and damage the reproductive system.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Finasteride helps hair growth but may cause sexual side effects and depression.

Larger prostate size in older men may be linked to poorer semen quality and fertility issues.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

Finasteride helps female-pattern hair loss.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.