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A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.

Increasing SSAT makes skin more prone to cancer.

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

Spironolactone helps regrow hair in women with hair loss.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Mouse genital development depends on male or female hormones for specific features.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

POMC-derived peptides are important for skin functions like immune response and stress management.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.

Spironolactone plus finasteride reduces hirsutism more effectively.

Researchers created hair-inducing human cell clusters using a 3D culture method.

Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.

The method effectively identifies banned substances in hair loss and skin disease cosmetics.

Combination drug therapy is effective for hirsutism that doesn't improve with just one medication.

Truncating mutations in the C2orf37 gene cause Woodhouse–Sakati syndrome.

Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Improved Finasteride delivery for hair loss treatment.

Spironolactone may help reduce excessive hair growth in women with high male hormone levels.

Nanoparticles with more oleic acid improved the delivery and stability of the drug spironolactone.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.