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Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Testosterone is crucial for development, growth, and various body functions in mammals.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

Eating less can improve stem cell function and increase lifespan.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

iPSCs can help treat genetic skin disorders by creating healthy skin cells from a small biopsy.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Enzymes called PADIs play a key role in hair growth and loss.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

Improved understanding of stem cell mechanisms can enhance skin tissue engineering.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.

Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.

Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Intermediate filaments are crucial for cell differentiation and stem cell function.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

Baby teeth stem cells can potentially grow organs and treat diseases.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

The PON1 192R gene variant is linked to a higher risk of psoriasis and heart disease in Western Mexico.

Found new possible treatments for hair loss.