151 citations
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July 2011 in “Archives of Dermatological Research” This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.
10 citations
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October 2009 in “Photomedicine and laser surgery” This study found that intense pulsed light treatment achieved a mean of 85% hair reduction in two patients with faun tail, although local anesthesia may be needed due to severe pain associated with neurological abnormalities.
December 2024 in “Pharmaceutics” This review systematically examined recent advancements in spironolactone-loaded nanocarriers, revealing that lipid and vesicular nanoparticles enhance bioavailability and skin penetration for treating androgen-dependent disorders, but highlighted the need for further clinical studies to optimize their use.
July 2024 in “Journal of Investigative Dermatology” ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.
2 citations
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October 2022 in “Rheumato” This case report from Tishreen Hospital highlights that although rare, cardiac tamponade and acute surgical abdomen due to acute peritonitis and ascites can occur concurrently as initial presentations of systemic lupus erythematosus.
31 citations
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July 1975 in “PubMed” This study reported that intensive immunosuppression in multiple sclerosis patients significantly reduced relapse rates versus pre-treatment expectations, though some required ongoing treatment after tapering.
4 citations
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February 2024 in “Anais Brasileiros de Dermatologia”
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses how activating the hexosamine pathway may enhance skin homeostasis by increasing hyaluronic acid secretion and supporting hair follicle stem cell self-renewal, but reports no new results.
February 2009 in “Journal of The American Academy of Dermatology” This study suggests that fractional infrared technology may effectively improve cervical skin laxity by enhancing dermal thickness without adverse effects in a small pilot group.
In this case study, an 80-year-old woman developed lichen planus pigmentosus inversus after receiving multiple intra-articular injections of a homeopathic preparation, suggesting a possible link, though causality remains speculative.
6 citations
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March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
January 2022 in “Faculty of 1000 Research Ltd” This case report documents digital gangrene as an unusual early sign of late-onset systemic lupus erythematosus in a 56-year-old man, which improved with rituximab treatment.
This case report highlights the growing prevalence and treatability of neurosyphilis, stressing the need to consider it in neurological symptoms such as encephalopathy, facial nerve palsy, and gelastic seizures associated with the frontal lobe.
5 citations
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May 2017 in “Journal of dermatological science” This study reviewed the genetic and phenotypic aspects of Olmsted syndrome, highlighting pathogenic mutations in TRPV3 and MBTPS2 genes and their association with specific skin manifestations like symmetrical keratoderma and hyperkeratotic plaques.
This study found that skin lesions in systemic lupus erythematosus patients are significant for diagnosis and prognosis, with malar rash and diffuse hair loss being common indicators of disease activity.
2 citations
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January 2024 in “Pakistan Journal of Life and Social Sciences (PJLSS)” This study examines the use of emulgel-based systems as drug delivery vehicles for hydrophobic medications, noting their potential benefits in dermatological applications due to properties like easy spreadability, non-greasy texture, and prolonged shelf life.
January 2025 in “Biomedical Reports” This case report describes the first successful use of telitacicept in treating a patient with systemic lupus erythematosus and a history of papillary thyroid carcinoma, suggesting its potential as a therapeutic option for such conditions.
December 2020 in “Forum Dermatologicum” In this case report, a combination treatment of intralesional triamcinolone acetonide, oral acitretin, and topical clobetasol propionate showed effectiveness in reducing symptoms of Graham-Little-Piccardi-Lasseur syndrome in one patient over two months, with no new areas of hair loss observed.
2 citations
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May 2024 in “Cureus” This study found that both single and double spin platelet-rich plasma methods significantly reduced chronic ulcer surface area, with single spin showing notable healing improvements.
March 2004 in “Journal of The American Academy of Dermatology” This report describes a unique case of dyschromatosis universalis in a 10-year-old Haitian male, notable for the presence of a silvery sheen to his scalp hairs and eyelashes, which may represent a variation of the condition.
138 citations
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November 2015 in “Journal of Pharmacology and Experimental Therapeutics” This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
August 2024 in “Journal of Clinical Medicine” This study evaluates the effectiveness of hydroxychloroquine in treating lichen planopilaris, suggesting varying success based on a real-life retrospective analysis.
Saw palmetto cream for hair loss works better with glycerol and sorbitol.
April 2026 in “Journal of Craniofacial Surgery” This pilot study found that plasma- and sonophoresis-assisted delivery of an exosome-containing formulation improved hair and scalp metrics over 12 weeks, with short-term safety observed, but controlled trials are needed for confirmation.
February 2026 in “Oncology Reviews” This review highlights the promising clinical outcomes of sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate for breast cancer that targets TROP2, demonstrating improved response rates and progression-free survival, with manageable safety concerns including primarily mild-to-moderate nausea and alopecia.
2 citations
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April 2012 in “American Journal of Dermatopathology” This report describes two cases of nevus lipomatosus superficialis with the unusual feature of dilated hair follicles, emphasizing the need for precise histopathological diagnosis to differentiate from similar conditions.
9 citations
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February 2002 in “International Journal of Dermatology” This case study reports that a combination of PUVA therapy and oral methyl prednisolone initially improved symptoms of a woman's cutaneous T-cell lymphoma but required ongoing treatment due to recurrence.
September 2022 in “Intisasi sains media” This case report describes a 22-month-old with alopecia universalis who showed improved hair growth after receiving combination therapy with minoxidil, corticosteroids, and excimer laser.
October 2022 in “Portuguese journal of dermatology and venereology” This case study reports significant improvement in severe atopic dermatitis and alopecia areata symptoms in a patient treated with dupilumab, highlighting the potential for patient selection in optimizing therapeutic outcomes.
7 citations
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March 2023 in “Journal of Investigative Dermatology” Low-intensity ultrasound may help protect hair follicles from chemotherapy-induced hair loss.