Mucin-Poor Follicular Mycosis Fungoides

February 2002 in “ International Journal of Dermatology ”

Mustafa Abdullah Özdemir, Cüyan Demirkesen, Nurcan Arzuhal, Yalçýn Tüzün

alopecia totalis follicular hyperkeratoses PUVA therapy methyl prednisolone CD3(+) T-cells CD4(+) T-cells beta 2 microglobulin steroid phototherapy

TLDR The patient's symptoms improved with treatment but recurred when the steroid dose was reduced, requiring ongoing therapy.

The document described a case study of a 49-year-old woman with mucin-poor follicular mycosis fungoides, presenting with generalized pruritus, erythema, alopecia totalis, and follicular hyperkeratoses. Histological examination revealed folliculocentric infiltration by atypical T-cells, primarily CD3(+) and CD4(+), with minimal mucin presence. Initial treatment with psoralen-UVA (PUVA) and oral methyl prednisolone led to partial improvement, including patchy hair regrowth and reduced pruritus. However, symptoms recurred after reducing the steroid dose, necessitating increased steroid dosage and resumption of PUVA therapy. The patient's condition was managed with ongoing treatment adjustments.

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Mucin-Poor Follicular Mycosis Fungoides

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