research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
Search
for
Sort by
Research
90-120 / 169 results 
research Red Ginseng Oil Promotes Hair Growth and Protects Skin Against UVC Radiation
Red ginseng oil may help grow hair and protect skin from UVC light.
research Dermatological Drugs, Topical Agents, and Cosmetics
The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.
research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis
GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
research Ligand-Independent Actions of the Vitamin D Receptor: More Questions Than Answers
The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.
research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Modulation of Hair Growth Promoting Effect by Natural Products
Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
research The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia
A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
research Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration During Wound Healing
Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
research Hair Growth Promotion and Anti-Hair Loss Effects of Arabica Coffee Pulp Extracts Using Supercritical Fluid Extraction
Arabica coffee pulp extract may help prevent hair loss and promote hair growth.
research A Non-Cell Autonomous Dermal Hedgehog Signaling Mechanism for Follicular Neoplasia and Induction
Mutations in the SHH pathway in certain skin cells can cause skin tumors and abnormal hair growth.
research Hair Growth and Restoration by Transcriptional Control of Tissue Regeneration in Cancer Recovery Process by Huaier
Huaier helps hair grow back and repairs tissue after cancer treatment.
research The Importance of Biomedical Engineers in the Health System
Biomedical engineers are crucial for developing better treatments for chronic and autoimmune diseases.
research Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration
The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
research Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.
research DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice
Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
research Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Hair, Aging, And Environment: Clinical Epidemiological Aspects
Environmental factors like smoking, UV exposure, and poor diet contribute to hair loss and graying, and lifestyle changes can help manage it.
research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research Cutaneous Reactions to Chemotherapeutic Drugs and Targeted Therapy for Cancer
Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.
research Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
Muscles and nerves that cause goosebumps also help control hair growth.
research Shampoos: Ingredients, Efficacy, and Adverse Effects
Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.
research Chemotherapy-Induced Alopecia Management: Clinical Experience and Practical Advice
The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.
research Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia
New genes found linked to balding, may help develop future treatments.
research Alopecia in Patients Treated with Molecularly Targeted Anticancer Therapies
Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.
research Role of Insulin Resistance and Diet in Acne
Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Polyamines and Hair: A Couple in Search of Perfection
Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
research Alopecia in Association with Malignancy: A Review
Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.
research Biochemistry of Epidermal Stem Cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Therapeutic Applications and Pharmacoeconomics of Microneedle Technology
Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.