41 citations
,
August 2024 in “Drug Delivery and Translational Research” This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.
35 citations
,
March 2005 in “Journal of Investigative Dermatology” In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.
32 citations
,
May 2012 in “PloS one” This study found that despite the persistence of aberrant double-negative T-cells, functional immune-competence was maintained after thymic transplantation in a patient with a rare FOXN1 mutation.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
29 citations
,
August 2005 in “Biopolymers” In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.
28 citations
,
October 2018 in “Clinical Obstetrics and Gynecology” This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.
27 citations
,
March 2018 in “Biomaterials” This study found that a cocktail of three proteins from embryonic skin can enable adult fibroblasts to regenerate hair follicles by altering gene expression and activating regenerative signaling pathways.
22 citations
,
November 2018 in “Brazilian Journal of Pharmaceutical Sciences” This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.
20 citations
,
January 2021 in “Plants” This review discusses the role of PIN-FORMED 2 and related signaling pathways in root hair growth regulation and reports no new experimental findings.
20 citations
,
April 1999 in “British journal of plastic surgery” This study found that using a ruby laser for hair removal resulted in a significant average reduction of 56.4% in hair density among participants dissatisfied with other methods.
19 citations
,
January 2018 in “Scientific Reports” This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.
18 citations
,
December 2016 in “Phytomedicine” In this study, applying 1% or 5% Curcuma aeruginosa essential oil lotion to the underarm for 10 weeks significantly slowed hair growth and brightened skin in young women, with no adverse effects reported.
17 citations
,
August 2024 in “Discover Nano” This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.
16 citations
,
March 2008 in “International journal of pharmaceutics” This study found that formulation factors like pH, viscosity, and chemical enhancers can significantly influence intrafollicular hydrocortisone permeation in vitro, with higher pH and enhancers reducing follicular contribution.
15 citations
,
December 2013 This study found that in men with androgenic alopecia, moderate to severe cases were associated with the AA genotype of rs1160312, blood vanadium concentrations, and regular consumption of soy bean drinks.
12 citations
,
December 2017 in “Food and chemical toxicology” This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
12 citations
,
February 2014 in “Recent Patents on Inflammation & Allergy Drug Discovery” This article reviews various aspects of shampoos, including preparation methods and commercial value, but reports no new experimental results, instead focusing on patents and product evaluation criteria.
11 citations
,
January 2004 in “Exogenous dermatology” This review discusses the impact of various external factors like cosmetics, traction, and radiation on hair health and color, but reports no new findings.
10 citations
,
April 1995 in “Animal Science/Animal science” This study found that melatonin implants advanced the timing of the spring moult and increased hair follicle activity in adult cashmere goats, but had no significant effects on juvenile goats.
8 citations
,
January 2021 in “Pharmaceutics” This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.
8 citations
,
July 2017 in “Biochemical and biophysical research communications” This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.
4 citations
,
May 2019 in “Asian Journal of Pharmaceutical Sciences” This study found that a dutasteride tablet formulation using cyclodextrin complex, solubilizing polymer, and surfactant achieved similar bioavailability in beagle dogs to that of a commercial capsule.
4 citations
,
August 2014 in “Journal of molecular structure” In this study, the authors concluded that a hydrolyzed eggwhite protein treatment promoted the reconnection of disulfide bonds in excessively bleached hair, after reduction and oxidation processes in permanent waving.
3 citations
,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This research suggests that innate lymphoid cells type 1 (ILC1) may contribute to the development of alopecia areata, alongside CD8+ T cells, by disrupting hair follicle immune privilege and promoting features of the disease.
2 citations
,
November 2024 in “AAPS PharmSciTech” In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.
2 citations
,
March 2023 in “Research Square (Research Square)” This review discusses existing forensic DNA phenotyping panels for biogeographical ancestry and externally visible characteristics and highlights major technical limitations, including terminology issues, genetic knowledge gaps, and technological debates; it reports no new results.
2 citations
,
July 2020 in “Journal of Applied Pharmaceutical Science” This study examined the preservative and antimicrobial susceptibility of non-fermenting bacilli collected from beauty salon waste in Brazil.
2 citations
,
August 2019 in “International Journal of Applied Pharmaceutics” This study explored the use of SOD-loaded niosomes as carriers to enhance the delivery of superoxide dismutase into hair follicles on guinea pig skin, finding that niosomes improved SOD penetration and preservation compared to free SOD, suggesting their potential as effective delivery vehicles.
2 citations
,
March 2019 in “European Journal of Dermatology” This study concluded that shampoos sold in pharmacies generally contain fewer regulated allergens under EU law compared to those sold in mass-market stores or by mail order, and pharmacy-sold baby shampoos were allergen-free.
2 citations
,
March 2017 in “Veterinary dermatology” This study demonstrated that herbal therapy with oil extract increased triglyceride content in dog hair, suggesting potential benefits on coat quality that require further investigation.