The Hair Loss Encyclopedia

Forensic DNA Phenotyping: A Review on SNP Panels, Genotyping Techniques, and Prediction Models

March 2023 in “ Research Square (Research Square) ”

Nuria Terrado-Ortuño, Patrick May

TLDR Forensic DNA phenotyping faces challenges due to inconsistent terminology, limited genetic understanding, and debates over technology and models.

This review examines forensic DNA phenotyping (FDP), focusing on single nucleotide polymorphism (SNP) panels, genotyping techniques, and prediction models. It identifies 48 panels for biogeographical ancestry (BGA), 43 for externally visible characteristics (EVC), and 15 for both. The review highlights the lack of harmonization in terminology and reporting, insufficient genetic knowledge, environmental influences on marker selection, and debates over genotyping technologies and prediction models. It aims to provide an updated guide and overview of current FDP literature, addressing the technical limitations and challenges in the field.

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