A Systematic Review of Randomized Controlled Trials Assessing Phytochemicals and Natural Ingredients for Skin and Hair Care

This systematic review evaluated 63 randomized controlled trials (RCTs) on phytochemicals and natural ingredients for skin and hair care, involving 3,439 subjects. It found significant improvements in skin conditions like melasma, hyperpigmentation, and acne, as well as hair growth and quality, with natural products such as Polypodium leucotomos, Camellia sinensis, and Centella asiatica. However, results varied across studies, and some interventions did not show significant effects. The review highlighted the potential benefits of natural ingredients but emphasized the need for larger and more robust RCTs to confirm their efficacy, noting concerns about biases and the generalizability of findings.