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      Hormone Replacement Therapy and the Skin

      research Hormone replacement therapy and the skin

      138 citations , May 2000 in “Maturitas”
      This review discusses the effects of estrogen on skin and reports no new clinical results; it highlights estrogen's potential benefits on skin thickness, collagen quality, and hair follicle life cycle.

      research Skin climacteric aging and hormone replacement therapy

      27 citations , March 2006 in “Journal of cosmetic dermatology”
      This review examines the effects of menopause on skin aging and suggests hormone replacement therapy may improve some symptoms, without providing new clinical findings.

      research [Hormone replacement treatment and skin aging].

      16 citations , October 1996 in “PubMed”
      This study concluded that hormonal replacement therapy can improve skin ageing symptoms by increasing skin thickness and alleviating dryness and hyposeborrhoea in postmenopausal women.

      research Managing Skin Ageing as a Modifiable Disorder—The Clinical Application of Nourella® Dual Approach Comprising a Nano-Encapsulated Retinoid, Retilex-A® and a Skin Proteoglycan Replacement Therapy, Vercilex®

      4 citations , March 2022 in “Cosmetics”
      This review suggests that a dual treatment approach using Nourella® cream with nano-encapsulated Retilex-A® and per-oral Vercilex® tablets may effectively improve skin thickness, elasticity, and overall rejuvenation in aging skin, as shown in interventional studies.

      research De novo hair morphogenesis in engineered skin substitutes

      1 citations , January 2012 in “OhioLink ETD Center (Ohio Library and Information Network)”
      This study demonstrates that trichogenic dermal papilla cells are crucial for hair regeneration in engineered skin substitutes, with adult murine cells showing higher activity than adult human cells.
      Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging

      research Stem cells and aberrant signaling of molecular systems in skin aging

      25 citations , November 2014 in “Ageing Research Reviews”
      This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.
      Skin Aging and Menopause: Implications for Treatment

      research Skin Aging and Menopause

      180 citations , January 2003 in “American Journal of Clinical Dermatology”
      This article reviews the effects of menopause on skin aging and suggests that hormone replacement therapy may help reverse some of these changes.
      Estrogens and Aging Skin

      research Estrogens and aging skin

      150 citations , April 2013 in “Dermato-endocrinology”
      This review discusses the effects of estrogen on skin aging and highlights potential therapies, but reports no new clinical findings.
      Estrogens and the Skin

      research Estrogens and the skin

      137 citations , June 2005 in “Climacteric”
      This review indicates that estrogen loss during menopause significantly impacts skin health, while estrogen treatment may increase skin collagen, thickness, and elasticity, though effects on other skin characteristics are inconsistent.
      EEMCO Guidance for the In Vivo Assessment of Skin Greasiness

      research EEMCO Guidance for the in vivo Assessment of Skin Greasiness

      137 citations , January 2000 in “Skin Pharmacology and Physiology”
      This review outlines the factors affecting skin greasiness and sebum production, highlighting measurement challenges but reports no new clinical findings; further research may guide sebosuppressive treatments for acne.
      Effect of Estrogens on Skin Aging and the Potential Role of SERMs

      research Effect of estrogens on skin aging and the potential role of SERMs

      120 citations , October 2007 in “Clinical Interventions in Aging”
      This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.
      Clinical and Biological Impact of the Exposome on the Skin

      research Clinical and biological impact of the exposome on the skin

      77 citations , July 2020 in “Journal of the European Academy of Dermatology and Venereology”
      This review examines the skin exposome, including solar exposure, air pollution, hormones, nutrition, and psychological factors, but reports no new clinical results.
      Skin Connective Tissue and Aging

      research Skin connective tissue and ageing

      77 citations , July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology”
      This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.
      Skin Aging

      research Skin ageing

      76 citations , May 2007 in “Menopause International”
      This review discusses the relationship between estrogen deficiency and skin aging in postmenopausal women, noting potential benefits of estrogen use on skin collagen and elasticity, but reports no new clinical results.
      The Effect of Menopause on the Skin and Other Connective Tissues

      research The effect of menopause on the skin and other connective tissues

      44 citations , October 2011 in “Gynecological Endocrinology”
      This review discusses the effects of oestrogen on skin ageing and highlights the need for large-scale clinical trials to evaluate postmenopausal oestrogen use, reporting no new findings.
      Skin, Hair, and Beyond: The Impact of Menopause

      research Skin, hair and beyond: the impact of menopause

      14 citations , April 2022 in “Climacteric”
      This review discusses the impact of HRT on menopausal skin and hair symptoms and argues that potential benefits should be part of informed decision-making for managing menopause.

      research Skin Changes and Its Care in Menopause

      January 2026
      In this chapter, the authors discuss how the decline in estrogen during menopause affects skin health, detailing changes like dryness, thinning, and increased sensitivity, and suggest management strategies such as lifestyle adjustments and hormone replacement therapy to address these issues.

      research MON-203 Dermatological Effects Of Hormone Replacement Therapy

      October 2025 in “Journal of the Endocrine Society”
      This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

      research Menopause and the Skin

      January 2000 in “Elsevier eBooks”
      Menopause can cause skin to become dry, less elastic, and more wrinkled due to lower estrogen levels.
      Skin Aging in Women: Pathophysiology and Treatment

      research Skin Ageing in Women: Pathophysiology and Treatment

      September 1999 in “The Journal of The British Menopause Society”
      This review discusses how menopause and hormone replacement therapy affect skin aging in women but reports no new clinical findings.