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Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Vitamin D receptor is crucial for starting hair growth after birth.

MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.

Mice with human skin protein K8 had more skin problems and cancer.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

CD98hc's role in skin health decreases with age.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Skin organoids are a promising new model for studying human skin development and testing treatments.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.