March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
131 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
108 citations,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
9 citations,
January 2018 in “Hair transplant forum international” Researchers concluded that safe hair follicle extraction limits in FUE vary by individual characteristics and proposed a method to calculate these limits to maintain appearance.
January 2018 in “Springer eBooks” Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.
114 citations,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
October 2016 in “Veterinary record case reports” A cat had a rare skin disorder with hair loss and scaling, linked to a suspected tumor.
2 citations,
September 2014 in “The American Journal of Cosmetic Surgery” Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.
60 citations,
September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
19 citations,
November 2018 in “Experimental Dermatology” The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
94 citations,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.
12 citations,
January 2005 in “Pediatric Dermatology” Fox Fordyce disease might be more common in prepubertal girls than thought and can be managed with treatment.
Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.
147 citations,
January 2003 in “American journal of clinical dermatology” The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
2 citations,
November 2022 in “Scientific reports” Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.
1 citations,
March 1985 in “Head & neck surgery” Hair-bearing punch grafting effectively repaired damage from artificial hair implants.
32 citations,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
5 citations,
March 2017 in “Cell and Tissue Banking” Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.
19 citations,
May 2007 in “Dermatologic therapy” The document concludes that various treatments, including laser therapy, are effective for managing pseudofolliculitis barbae, especially in darker skin types.
24 citations,
August 2022 in “Immunity” Type 2 immunity helps control mite growth in hair follicles, preventing damage.
A neck lesion misdiagnosed as benign was later treated successfully with Mohs Micrographic Surgery.
2 citations,
June 2018 in “Advances in Cosmetic Surgery” Neck rejuvenation involves tailored techniques to improve skin, muscle, and fat appearance.
December 2019 in “Journal of pediatrics & neonatology” A 13-year-old boy had a rare, stable type of hair loss with little chance of regrowth, but treatment is available for looks.
35 citations,
October 2019 in “Journal of pediatric health care” Children with darker skin tones can have specific skin conditions that need tailored treatments.
3 citations,
April 2015 in “International research journal of pharmacy” Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
40 citations,
December 2015 in “Stem Cells International” Mesenchymal stem cells help improve wound healing by reducing inflammation and promoting skin cell growth and movement.