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Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Fractional CO2 laser treatment significantly boosts drug and nanoparticle skin absorption, especially through hair follicles.

Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.

RXR-alpha is strongly expressed in both normal and psoriatic skin and may help in skin cell differentiation and hair growth.

P2X₃-IR fibers are widespread in rat skin and likely help detect pain.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Prolactin may be important for skin growth and immune function.

Mature cells can re-enter the cell cycle and potentially lead to cancer.

Smaller particles of the drug carrier penetrated skin better, with 300 nm size being best for targeting hair follicles.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Male skin gets drier and more alkaline as it ages, which may need different skincare than women's skin.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

MicroRNAs could improve skin tissue engineering by regulating cells and changing the skin's bioactive environment.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.

Raspberry ketone may help grow hair and improve skin elasticity.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.