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The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Improved understanding of stem cell mechanisms can enhance skin tissue engineering.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

The project created a standardized system for classifying skin lesions in lab rats and mice.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Scientists created stem cells that can grow hair and skin.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Wnt signaling is crucial for skin development and hair growth.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Dermoscopy is effective for diagnosing various skin infestations and infections.

Looking at tissue characteristics isn't reliable for telling apart basal cell carcinoma from certain benign skin tumors.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

The document says that hair loss in women is often due to androgenic alopecia, similar to male baldness, and that hirsutism is treated with hormonal and cosmetic methods.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Different types of stem cells and their environments are key to skin repair and maintenance.