November 2025 in “Journal of Investigative Dermatology” Radiation-induced hair loss may be caused by hair growth stopping and inflammation in blood vessels.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that deleting Ube2n in adult mouse skin leads to inflammation and other skin changes, and identifies IRAK1/4 as potential treatment targets for inflammatory skin disorders.
21 citations
,
January 1995 in “Molecular Biology Reports” This study identified a novel human type I hair keratin, hHa3-II, as an isoform of a previously described hHa3 keratin, with distinct sequence differences indicating separate gene encoding.
17 citations
,
February 2015 in “Experimental Dermatology” This report expands the known genetic mutations linked to monilethrix by identifying new patients with KRT83 mutations, confirming its role as a causative gene for this hair disorder.
September 2024 in “Genes” This study found significant genetic differences between pigs with and without hair whorls, suggesting potential implications for pig breeding strategies in China.
4 citations
,
December 2023 in “Medicine” This study found that the genes MYLK and CALD1 were expressed at lower levels in bladder cancer and osteosarcoma tissues compared to normal tissues, and their expression levels appeared to correlate with poorer survival outcomes, suggesting they may be important in disease progression and prognosis.
This study found that innate lymphoid cells-type 1 (ILC1) can induce alopecia areata by disrupting hair follicle immune privilege without the involvement of classical CD8+ T cells.
7 citations
,
March 2023 in “Arabian Journal of Chemistry” This study suggests that cepharanthine may play an important role in treating SARS-CoV-2 infection by targeting multiple pathways and related targets associated with COVID-19.
September 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, DHT inhibited hair regrowth and promoted hair follicle miniaturization in mice, with skin-resident myeloid cells enhancing their interaction with hair follicular cells, especially in females.
June 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in alopecia areata, epidermal γδ T cells and macrophages contribute to the disease alongside CD8 T cells, with the expression of BST2 marking interferon-driven immune activation in both mouse and human skin, which decreases following treatment with the JAK inhibitor tofacitinib.
101 citations
,
December 2014 in “Stem Cells and Cloning Advances and Applications” This article reviews the potential and current applications of adult oral stem cells in regenerative medicine, highlighting promising animal model results but noting that few human clinical trials have yet been conducted.
4 citations
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March 2024 in “Cells” This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.
13 citations
,
March 2020 in “Acta veterinaria Scandinavica” This study found that wounds in dogs treated with allogeneic adipose-derived mesenchymal stem cells showed faster and improved healing compared to wounds receiving conventional treatment.
1 citations
,
November 2022 in “Journal of Dermatological Treatment” This review discusses the use of platelet-rich plasma for various dermatologic conditions but reports inconsistent evidence and a lack of standardized protocols; patients often report high satisfaction despite mixed clinical outcomes.
June 2024 in “Clinical and Experimental Obstetrics & Gynecology” In this study, women with recurrent implantation failure after IVF/ICSI had significantly lower platelet, plateletcrit, and lymphocyte counts, but these parameters were not effective for predicting the condition.
January 2023 in “Revista CPAQV - Centro de Pesquisas Avançadas em Qualidade de Vida” This study reviewed clinical literature on telogen effluvium caused by COVID-19 and found that intense hair shedding predominantly affected women, typically developing two months post-infection and resolving within one to four months.
74 citations
,
August 2023 in “Frontiers in Immunology” In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.
6 citations
,
November 2022 in “Development” This review discusses the developmental origins and diversity of dermal fibroblasts, focusing on their roles in epidermal and hair follicle growth, but reports no clinical results.
2 citations
,
May 2024 in “International Journal of Molecular Sciences” This study found that in a mouse model of psoriasis, depleting CD169+ macrophages led to milder symptoms and decreased inflammation, suggesting these macrophages play a crucial role in psoriasis development.
1 citations
,
December 2025 in “Journal of Investigative Dermatology” Photocrosslinkable biomaterials can improve wound healing by controlling mechanical environments.
11 citations
,
June 2024 in “Clinical ophthalmology” This study highlights that Demodex mites, commonly found on human skin, can cause significant eye and skin issues such as blepharitis, rosacea, and dermatitis when present in abnormally high densities, underscoring the need for targeted management strategies.
7 citations
,
April 2004 in “International Journal of Dermatology” This report describes a case of epidermolytic hyperkeratosis in a newborn and her mother, both possessing a specific KRT1 gene mutation known to cause this skin disorder.
6 citations
,
April 2022 in “Biomedicine & pharmacotherapy” This review discusses the potential of using triads of repositioned medicines targeting multiple pathogenic mechanisms to prevent or delay retina degeneration, but reports no new results.
January 2026 in “AppliedMath” This study explored a mechanism for making Turing pattern formations more predictable and robust by isolating pattern modes to prevent their sensitivity to initial conditions, which can lead to different outcomes from minor initial changes.
January 2019 in “Annals of Dermatology” This study observed that in Korean HIV patients, tinea infection, folliculitis, and seborrheic dermatitis were the most common skin diseases, with HAART medications generally reducing folliculitis incidence. Skin disease prevalence differed by immune status, affecting treatment needs.
11 citations
,
June 2017 in “Journal of cell science” In this study, researchers found that AGD1 is crucial for membrane recruitment during root hair development in Arabidopsis thaliana, with its pleckstrin homology domain essential for targeting specific plasma membrane regions.
5 citations
,
April 2019 in “Phytochemical Analysis” This study developed a sensitive and precise scFv-based ELISA for miroestrol quantification, aiding quality control in P. candollei plant materials and health supplements.
1 citations
,
July 2017 in “Microbial Cell Factories” This study found that supplementing soybean oil significantly increased the production of the cyclosporine A derivative [(4'-OH)MeLeu]4-CsA by 55.6%, offering potential enhancements for its clinical application.
6 citations
,
November 2010 in “Histochemistry and cell biology” This study found that transthyretin and megalin expression in human scalp hair follicles varies significantly with the hair growth cycle, peaking during anagen and diminishing in catagen and telogen phases.
2 citations
,
June 2023 in “Journal of cell science” In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.