5 citations
,
July 2020 in “Journal of the American Academy of Dermatology” This study suggests that using antihistamines alongside a regimen of topical corticosteroid and superficial cryotherapy may enhance hair regrowth in patients with mild to moderate alopecia areata.
2 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study provides the first draft of the male Asiatic lion's whole genome, revealing low genomic diversity and highlighting conservation concerns.
2 citations
,
October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics” Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
March 2026 in “Calcified Tissue International” This review discusses the complex role of the EDA pathway in vertebrate skeletal development, emphasizing its interaction with other morphogenic pathways to influence skeletal diversity, but reports no new experimental results.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified a new cis-regulatory element in the mouse Hr gene that influences its expression in skin and brain cells, highlighting a complex molecular network involved in hair follicle formation.
July 2004 in “British Journal of Dermatology” This paper summarizes the main findings presented in the plenary sessions of the British Journal of Dermatology, July 2004 issue, and provides no new research results.
152 citations
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March 1988 in “Journal of The American Academy of Dermatology” In this study, a unique form of chronic superficial pyoderma gangrenosum with verrucous and ulcerative lesions was reported to heal without systemic corticosteroids in most patients.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
173 citations
,
August 2015 in “Developmental cell” This study characterizes gene expression patterns in embryonic hair follicle progenitors and their niche, identifying signaling pathways like axon guidance that may drive cellular rearrangements for hair follicle formation.
February 2026 in “iScience” This study found distinct hair metal profiles in Parkinson's disease patients, with lower iron and copper, higher manganese and arsenic, and explored their link to gut dysfunction and microbiota dysbiosis, suggesting hair metal analysis as a promising diagnostic tool.
September 2024 in “Heliyon” In this study, researchers observed that even a single session of hair dyeing can damage hair fibers, with significant worsening of mechanical properties and protein composition after three or more consecutive treatments, emphasizing the need to consider the cumulative impacts of dyeing on hair health.
25 citations
,
June 2022 in “Developmental cell” In this study, Hedgehog signaling in dermal papilla fibroblasts was found to accelerate hair growth and induce follicle multiplication in mice via the SCUBE3/TGF-β pathway, with some effects observed in human scalp hair follicles.
3 citations
,
October 2024 in “All Life” In this review, the researchers identify and discuss promising molecular and genetic targets for lung cancer therapy, suggesting that advancements in understanding these targets could lead to new drug developments and more effective treatments.
November 2025 in “Journal of Investigative Dermatology” PCFCL may have unrecognized subtypes and needs more research.
13 citations
,
August 2024 in “iScience” This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.
118 citations
,
October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
29 citations
,
February 2022 in “Frontiers in Cell and Developmental Biology” This review discusses strategies to improve CRISPR/Cas systems by addressing limitations like off-target effects and delivery inefficiencies, offering practical guidance and highlighting future applications, but reports no new research findings.
260 citations
,
June 2011 in “Cell” This study found that Wnt signaling in the hair follicle is crucial for coordinating the behavior of epithelial and melanocyte stem cells, which drives hair regeneration and melanocyte differentiation in mice.
1201 citations
,
January 2010 in “Science” This review discusses stem cells in the hair follicle, bone marrow, and intestinal epithelium and introduces a model where quiescent and cycling stem cells may coexists in "zoned" configurations.
109 citations
,
October 2007 in “American Journal of Human Genetics” This study found that postnatal treatment with recombinant EDA normalized adult teeth, improved sweating, and restored normal lacrimation in dogs with XLHED, suggesting its potential as a treatment for the condition.
5 citations
,
August 2021 in “Frontiers in Cell and Developmental Biology” This study found that DHEA along with osteogenic induction medium significantly promotes the osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells from older individuals.
5 citations
,
October 2017 in “Cellular Reprogramming” This research found that inhibiting HSP90 in a murine model increased cellular plasticity, suggesting a potential role for HSP90 in cancer progression through enhanced adaptability to stress.
62 citations
,
July 2022 in “Science Immunology” This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.
August 2023 in “International Journal of Molecular Sciences” This review discusses the use of human-to-mouse xenografting to study human skin processes in vivo, highlighting its importance for understanding skin regeneration and pathology while identifying knowledge gaps and challenges in applying these findings to human skin.
January 2026 in “Experimental Dermatology” The study suggests that refractory chronic alopecia areata cases have more infiltrating skin resident memory T cells, and using a JAK inhibitor may be an effective treatment option.
This study introduced a new computational method for simulating vibrational frequencies, finding that the multi-molecular fragment model showed the best agreement with experimental data for Finasteride, Lamivudine, and Repaglinide, outperforming traditional models in accuracy.
April 2023 in “Journal of Investigative Dermatology” The study identified increased IL-24 expression in keratinocytes and fibroblasts exposed to particulate matter, contributing to skin aging by promoting conditions similar to age-related changes such as increased MMP1 expression and decreased type I collagen production.
July 2025 in “Journal of Investigative Dermatology” Miniaturized hair follicles in androgenetic alopecia show abnormal mitochondrial activity and damage.
June 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The researchers reported that basement membrane heterogeneity, especially laminin α5 composition, plays a critical role in distinct inter-tissue interactions and hair cycle regulation in mouse hair follicles.
8 citations
,
December 2017 in “Small Ruminant Research” This study reports that variation in the ovine TCHH gene may influence wool fibre curvature, with specific gene variants affecting the mean fibre curvature in sheep.