78 citations
,
August 2002 in “Experimental Dermatology” This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.
76 citations
,
December 2011 in “Journal of Cell Science” This study found that keratins have evolutionarily conserved and domain-selectively enriched amino acids, which likely reflect their unique structural roles, with distinct patterns observed among epidermal, hair, and simple-type epithelial keratins.
8 citations
,
January 2018 in “Journal of Analytical Methods in Chemistry” This study developed a reliable HPLC-UV/Vis method to determine aluminum phthalocyanine chloride in skin, supporting its use in skin permeation studies for photodynamic therapy of cutaneous tumors.
1 citations
,
October 2022 in “Curēus” This case report highlights the challenges in diagnosing simple-virilizing congenital adrenal hyperplasia, emphasizing the importance of early expert evaluation to prevent irreversible changes such as virilization.
June 2023 in “Medicine and Pharmacy Reports” A woman with a specific mutation causing adrenal gland issues faced fertility problems, but careful hormone therapy helped her manage it successfully.
April 2020 in “The Egyptian Journal of Plastic and Reconstructive Surgery” In this retrospective study of 29 patients with scalp burn alopecia, researchers utilized a simple method involving tissue expansion to reconstruct the temporal and lateral sideburn areas, resulting in satisfactory, symmetrical, and standardized aesthetic outcomes according to both objective and subjective evaluations.
January 2017 in “Journal of Chemical Biological and Physical Sciences” This study found that human hair keratin genes contain a few simple sequence repeats, with one repeat in the exon of KRT31 and additional repeats in introns, varying in length compared to their orthologues.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
November 2024 in “Pharmaciana” This study found that the optimum formula for chia seed oil nanoemulsion hair serum, composed of 33.52% Tween 80 and 46.48% propylene glycol, meets good physical characteristics and stability requirements.
September 2024 in “Sasambo Journal of Pharmacy” This study formulated and tested a pomegranate leaf shampoo with antifungal properties, identifying an optimal composition of 5.5% SLS and 15.5% cocamide DEA, showing good foam stability, appropriate pH, and viscosity in lab tests.
2 citations
,
January 2020 The document describes a method for preparing hair for microscopy by embedding it in plastic, cutting it, and storing it cold before imaging.
1 citations
,
September 2024 in “Scientific Reports” This study observed that bacterial communities on scalp hair collected through non-invasive swabbing showed similar diversity and composition to those obtained by cutting or removing hair, suggesting that swabbing is an effective method for microbiome analysis on hair.
120 citations
,
June 2008 in “American Journal of Epidemiology” This study reported a 6.3% prevalence of PCOS among women in a Sri Lankan community, with most cases presenting as oligo/amenorrhea and polycystic ovaries.
109 citations
,
April 1997 in “Archives of Dermatological Research” The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.
48 citations
,
April 2019 in “ACS Applied Materials & Interfaces” In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.
44 citations
,
June 2018 in “Journal of Visualized Experiments” This paper presents a culturally informed protocol designed to improve the collection of hair samples from African Americans for cortisol measurement, illustrating its application with community-based study data.
39 citations
,
December 2012 in “The American Journal of Human Genetics” This study identified mutations in the SNRPE gene that may disrupt hair growth, linking a spliceosome component to hereditary hair loss disorders.
16 citations
,
November 2009 in “Experimental dermatology” This study found that ionizing irradiation significantly inhibits proliferation and induces apoptosis in human hair follicle keratinocytes, suggesting its potential as a preclinical assay system for testing radioprotectants.
13 citations
,
December 2001 in “Journal of Investigative Dermatology” This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.
12 citations
,
September 2020 in “Nanomaterials” This study found that centrifugally spun scaffolds with higher concentrations of platelet-derived bioactive molecules enhanced melanocyte metabolic activity and proliferation, suggesting potential for improving vitiligo treatment.
12 citations
,
July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
11 citations
,
September 1990 in “Clinical Endocrinology” This study found that girls with prepubertal simple hypertrichosis had significantly higher plasma levels of dihydrotestosterone compared to controls, which does not align with other androgen markers and warrants further investigation.
10 citations
,
January 1971 in “The American midland naturalist” A simple method can show hair's surface pattern.
9 citations
,
January 1999 in “Dermatology” Acyclovir can prevent rejection of skin grafts in herpes-related lip leucoderma.
8 citations
,
July 2018 in “Analytical sciences” This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
8 citations
,
January 2015 in “Clinical and Experimental Dermatology” This study found that an improved flap model in nude mice significantly reduces the time needed for hair induction compared to the traditional method, likely due to enhanced blood supply at the transplantation sites.
8 citations
,
July 2013 in “PLoS ONE” This study found that a new method using enzymatic laundry powder effectively extracts DNA from hair shafts, showing promise for genome-wide DNA analyses.
7 citations
,
May 1979 in “Medical & biological engineering & computing” The trichometer accurately measures hair growth and is easy to use.
4 citations
,
January 2020 in “Indian dermatology online journal” This report describes two scalp lichen simplex chronicus cases with hair loss and intense itching, noting unique dermoscopic and histopathological features.
3 citations
,
November 2022 in “Separations” This study successfully established and validated a method using LC-MS/MS to measure multiple androgens in plasma, finding that individuals with acne had higher levels of certain androgens compared to those with obesity.