research Parry Romberg Syndrome: When the Diagnosis of a Rare Disease Is Made in the Primary Care Setting
Parry Romberg syndrome requires awareness and teamwork in primary care for proper diagnosis and management.
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research Androgens and Erythropoiesis: Induction of Erythropoietin-Hypersecretory State and Effect of Finasteride on Erythropoietin Secretion
Androgens increase EPO production, finasteride doesn't significantly impact it.
research Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 from Relevant Ethno-Pharmacological Plants via In Silico Techniques
Three natural compounds from Ghanaian plants may help treat BPH and alopecia.
research Chemical Characterization and Ameliorating Effect of Centratherum Anthelminticum Extract Against Polycystic Ovary Syndrome in Wistar Rats
Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.
research Finasteride Treatment and Male Breast Cancer: A Register-Based Cohort Study in Four Nordic Countries
Finasteride use may increase the risk of male breast cancer.
research Analyzing Finasteride Data
Finasteride slightly improves prostate symptoms but has minimal difference from placebo.
research Discussion of 'A Hybrid Phase I-II/III Clinical Trial Design Allowing Dose Re-Optimization in Phase III' by Andrew G. Chapple and Peter F. Thall
The new clinical trial design is promising but needs real-world trials to test its effectiveness and possible enhancements.
research Comparison of Finasteride, a 5α Reductase Inhibitor, and Various Commercial Plant Extracts in In Vitro and In Vivo 5α Reductase Inhibition
Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
research Propranolol in the Treatment of Infantile Hemangioma: Clinical Effectiveness, Risks, and Recommendations
Propranolol is effective and safe for treating infantile hemangioma, but more research is needed for dosing and monitoring guidelines.
research Pain in Pancreatic Cancer: A Medical Oncologist's View
Pancreatic cancer pain management is inadequate due to the disease's severity and limited effectiveness of treatments.
research Finasteride
Finasteride caused serious side effects and led to six suicides.
research Metabolism of Finasteride in Rat Hepatic Microsomes: Age and Sex Differences and Effects of P450 Inducers
Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.
research Activity of Sorafenib Against Desmoid Tumor/Deep Fibromatosis
Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
research Assessment of Chemokines MIP-1α and MIP-1β in Iraqi Women with Polycystic Ovarian Syndrome
PCOS is linked to low-grade chronic inflammation.
research An Investigation Into the Frequency of Use of Traditional and Complementary Medicine in Patients Presenting to the Dermatology Clinic: A Survey Study
Some dermatology patients in Turkey use traditional medicine, with herbal remedies being most common, but these treatments can have mixed results and risks.
research Efficacy and Safety of 5 Alpha-Reductase Inhibitor Monotherapy in Patients with Benign Prostatic Hyperplasia: A Meta-Analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research A Meta-Analysis of the Evidence for Assisted Therapy with Platelet-Rich Plasma for Atrophic Acne Scars
Platelet-rich plasma therapy helps improve atrophic acne scars.
research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders
Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
research Effect of Finasteride on Human Testicular Steroidogenesis
research Multidimensional Assessment of Adverse Events of Finasteride: A Real-World Pharmacovigilance Analysis Based on FDA Adverse Event Reporting System (FAERS) from 2004 to April 2024
Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.
research The Structure of the Cornified Claw Sheath in the Domesticated Cat (Felis Catus): Implications for the Claw-Shedding Mechanism and the Evolution of Cornified Digital End Organs
Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.
research Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade
Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.
research A Review of the Evidence for and Against a Role for Mast Cells in Cutaneous Scarring and Fibrosis
Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
research Novel Approach with Fractional Ultrapulse CO2 Laser for the Treatment of Upper Eyelid Dermatochalasis and Periorbital Rejuvenation
The fractional ultrapulse CO2 laser is a safe and effective non-surgical treatment for upper eyelid issues and brow lifting.
research Urological Oncology: Prostate Cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors and has side effects; biopsy methods have similar outcomes; psychosocial factors affect sexual recovery post-surgery.
research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor
Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
research 5-Alpha-Reductase Inhibitors for Prostate Cancer Chemoprevention: An Updated Cochrane Systematic Review
5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.
research Urethral PSA Production After Radical Prostatectomy
After prostate removal surgery, higher initial prostate size was linked to higher urethral PSA levels and more severe male pattern baldness.
research Molecular Targeted Therapies for Cancer: Sorafenib Monotherapy and Its Combination with Other Therapies
Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.