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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

PCOS is caused by both genetics and environmental factors like diet and obesity.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

Hair loss needs more research for better treatments.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Finasteride effectively treats baldness but may cause sexual side effects.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Mutant mice help researchers understand hair growth and related genetic factors.