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The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Men with male pattern baldness have a higher risk of aggressive prostate cancer and benign prostatic hyperplasia.

A new method accurately measures nine specific hormones in human blood.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.