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Glossary Sex Determination

biological process deciding male or female development based on genetics

Sex determination is the biological process by which an organism develops as male or female, typically based on genetic factors. In humans, this is usually controlled by the presence of specific sex chromosomes: XX for females and XY for males. This process influences various physiological traits, including hair growth patterns and susceptibility to conditions like androgenetic alopecia.

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research Targeted Determination of Residual Sex Hormones in Cosmetics Using Magnetic Solid-Phase Extraction with Isotope-Labeled Internal Standards by UHPLC-MS/MS

December 2025 in “Molecules”

This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.

research Determination of some sex hormones in health supplements by liquid chromatography with tandem mass spectrometry

December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)”

This study developed a liquid chromatography with tandem mass spectrometry method to detect sex hormones in health supplements from Hanoi, Vietnam, finding three out of 16 samples contained sex hormones, including banned testosterone at low levels (~0.5 mg/kg).

research Determination of concentrations of sex steroids in blood plasma and semen of male dogs treated with delmadinone acetate or finasteride.

4 citations , January 2001 in “PubMed”

This study found that delmadinone acetate and finasteride caused a reversible suppression of prostate gland activity in male dogs, with delmadinone acetate also temporarily altering epididymal sperm maturation.

research Gender determination in sport

April 2022 in “Zbornik radova Pravnog fakulteta u Splitu”

This article discusses the challenges and legal developments in sex verification in sports, highlighting issues of fairness, discrimination, and the inadequacy of binary gender concepts; it reports no new results.

research Sex-limited chromosomes and non-reproductive traits

10 citations , July 2022 in “BMC Biology”

This review discusses how sex-limited chromosomes can affect non-reproductive traits in various sex determination systems and reports no new empirical results.

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community Dutasteride causing us to have… girl babies?

in Finasteride/Dutasteride 26 upvotes 3 years ago

User Kylo313 used dutasteride for 20 years and had two daughters, questioning if dutasteride affects the likelihood of having male vs female children. Replies mostly request hairline photos and discuss anecdotal experiences, with some suggesting correlation doesn't imply causation and that gender determination isn't affected by dutasteride.

community How are people getting DUT so easily?

in Finasteride/Dutasteride 15 upvotes 1 year ago

Dutasteride is hard to get in Europe due to prescription rules, leading some to consider online pharmacies or travel. Users discuss alternatives like private doctors and compare it to finasteride, expressing concerns about side effects and effectiveness.

community Sexual Sides? Are you sure you don't masturbate too much?

13 upvotes 9 years ago

Finasteride can cause sexual side effects, and reducing porn and masturbation may help improve sexual function. Some users experience persistent issues even after stopping finasteride.

community The Placebo Group Has It Worse Than The Standard Prescription 0.5mg Group. -The fear is all in your head.

190 upvotes 11 months ago

Dutasteride at 0.5mg may have fewer sexual side effects than expected, with many side effects attributed to psychological factors (nocebo effect). The placebo group experienced more side effects, suggesting fear and anxiety might contribute to perceived side effects.

community New warning by FDA on topical finasteride

in Research/Science 194 upvotes 1 year ago

The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

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