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Gender differences affect allergy prevalence, severity, and response to environmental toxins, with women often more affected than men.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Testosterone's effects on COVID-19 are unclear and need more research.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

Chinese women with PCOS have higher androgen levels, which change with age and weight.

Hormonal imbalances are important in the development of male pattern baldness.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

Older men with lower levels of available testosterone are more likely to be frail.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Anti-Müllerian hormone is a specific marker for ovarian issues in women with conditions like PCOS.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.