research Does Inhibition of Aldose Reductase Contribute to the Anti-Inflammatory Action of Setipiprant?
Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.
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research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)
The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
research Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial
Setipiprant did not significantly improve hair growth in men with hair loss.
research A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth
The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
research New Drugs Under Investigation for the Treatment of Alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
research The State-of-the-Art in the Management of Androgenetic Alopecia: A Review of New Therapies and Treatment Algorithms
New and existing treatments for hair loss show promise, with some being more effective for men and others for women.
research The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth
Targeting the PGD2-DP2 pathway may help treat hair loss.
research Peri-Xanthenoxanthene (PXX): A Versatile Organic Photocatalyst in Organic Synthesis
PXX is an effective and affordable photocatalyst for creating new chemical bonds in organic synthesis.
research Formulation of Hair Tonic from Ethanol Extract, Ethanol Fraction, and Chloroform-Methanol Fraction of Secang Wood (Caesalpinia sappan L.)
Secang wood extract hair tonic promotes hair growth and meets quality standards.
research Combination of Candlenut Oil Nanoemulsion and Celery Leaf Powder on Alopecia Disease Model
Candlenut oil and celery powder improved hair growth and could be a potential treatment for alopecia.
research Hair Tonic Activity Test of Ethanol Extract, n-Hexane Fraction, Ethyl Acetate, and Water of Ceiba Leaf (Ceiba Pentandra L. Gaertn) as Hair Growth Promoter on New Zealand Rabbits
Ceiba leaf extracts significantly speed up hair growth.
research Activity Test of Creambath Preparation of Waru Leaf Extract (Hibiscus tiliaceus L.) on Hair Growth in New Zealand White Rabbits
Waru leaf creambath can speed up hair growth in rabbits, especially at 37.5% concentration.
research Dermoscopic Findings of Alopecia in Patients with Hypothyroidism
People with hypothyroidism and hair loss often have more hair and scalp issues than those without thyroid problems.
research Dermapen Treatments for Healing Pockmarked Skin in Male Wistar Rats (Rattus Norvegicus): A Study Comparing Platelet-Rich Plasma with Salmon DNA Serum
PRP heals pockmarked skin better than salmon DNA serum.
research A 15-Year-Old Girl with Trichorhinophalangeal Syndrome Type 1 and Non-Ossifying Fibroma in Femur: A Case Report
A girl with a rare genetic disorder had a unique bone condition, highlighting the need for careful diagnosis and suggesting the disorder might be more common than thought.
research Anti-Alopecia Activity of Alkaloids from Noni Fruit Against Dihydrotestosterone-Induced Male Rabbits and Its Molecular Mechanism: In Vivo and In Silico Studies
Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.
research Glucocorticoid-Induced Side Effects Cause Oral Lesions in Systemic Lupus Erythematosus: A Case Report
Glucocorticoid treatment in lupus can cause oral lesions, which need early diagnosis and comprehensive care.
research Evaluation of the Use of Cyclophosphamide in Children Diagnosed with Steroid-Resistant Nephrotic Syndrome Treated at Fatmawati Hospital
Cyclophosphamide helped 59.4% of children with steroid-resistant nephrotic syndrome but caused side effects in 40.6%.
research Case Report: Disorder of Sex Development 46, XY with Proximal Hypospadias in a 10-Year-Old Twin Boy
A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.
research Effect of Ethanol Extract from White Skin of Watermelon (Citrullus Lanatus (Thunb.)) and Liquid from Trunk of Kepok Banana (Musa Acuminata x Musa Balbisiana (ABB Group)) on Hair Growth in Male White Rats
The combination of watermelon skin extract and banana trunk liquid promotes hair growth in male white rats.
research Potential Herbal Medicine for Alopecia Areata Treatment: A Systematic Review
Herbal medicine might be a good alternative for treating hair loss.
research Evaluation of Platelet Rich Plasma for Treatment of Female Pattern Hair Loss: A Placebo-Controlled Case Study
Platelet Rich Plasma (PRP) treatment significantly improved Female Pattern Hair Loss in a study, but more trials are needed for confirmation.
research Ethnobotany, Phytochemistry, and Pharmacology of the Mediterranean Dwarf Palm (Chamaerops Humilis L.)
The Mediterranean dwarf palm has medicinal, nutritional, and craft uses, but more research is needed.
research Causes and Management of Pica Disorder Among Central Iraqi Peoples
Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.
research Microemulsion Formulation of Combination of Virgin Coconut Oil and Rice Bran Oil for Hair Growth
The combination of virgin coconut oil and rice bran oil in the FIII formula promoted hair growth effectively.
research Formulation of Hair Tonic with Ethanol Extracts of Moringa Oleifera and Nephelium Lappaceum Leaves for Hair Growth
Hair tonic with equal parts Moringa and rambutan leaf extracts grew rabbit hair longer and heavier than the control product.
research Effect of Aloe Vera Leaf Extract on Healing of Incision Wounds in Rabbit Skin
Aloe vera extract speeds up wound healing in rabbits.
research The Rotterdam Study: 2012 Objectives and Design Update
The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.
research Androgenetic Alopecia: An Update Of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
research Physiological Functions of PP2A: Lessons from Genetically Modified Mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.