Glucocorticoid-Induced Side Effects Cause Oral Lesions in Systemic Lupus Erythematosus: A Case Report

This case report details a 30-year-old female with systemic lupus erythematosus (SLE) who developed oral lesions due to glucocorticoid treatment. The lesions, diagnosed as lupus cheilitis with HSV-1 infection, oral discoid lupus erythematosus, and palatal erythematous ulcer, were managed through a multidisciplinary approach involving internal medicine, dermatology, and oral medicine. Treatment included methylprednisolone, antiviral and antifungal agents, and supportive care, leading to resolution of the lesions by day 40. The report underscores the importance of early diagnosis and comprehensive management of glucocorticoid-induced side effects in SLE to enhance patient quality of life and prevent complications.