Dermoscopic Findings of Alopecia in Patients with Hypothyroidism

October 2022 in “ international journal of endocrinology and metabolism ”

Kaveh Gharaei Nejad, Behrang Motamed, Afagh Hassanzadeh Rad, Elahe Rafiee, Setila Dalili, Atrie Molaei

alopecia hypothyroidism androgenetic hair loss hair shaft abnormalities vellus hair scale abnormalities vascular changes dermoscopic signs inflammation hair loss inflammatory processes

Studysummary This study found that patients with hypothyroidism and hair loss exhibited significant differences in dermoscopic findings, including hair shaft abnormalities and vascular changes, compared to euthyroid individuals. Our plain-language summary of this paper — not a Tressless recommendation.

The cross-sectional study "Dermoscopic Findings of Alopecia in Patients with Hypothyroidism" involved 164 patients, 82 with hypothyroidism and hair loss, and 82 euthyroid individuals with androgenetic hair loss. The study found that hair shaft abnormalities, decrease in vellus hair, scale abnormalities, and vascular changes were significantly more prevalent in hypothyroid patients. The chances of these conditions increased by 2.02, 2.73, 3.53 times, respectively, in the hypothyroid group compared to the euthyroid group. The study concluded that dermoscopic signs of inflammation were detected in hypothyroid patients with hair loss, suggesting possible inflammatory processes. However, further investigations are needed due to a shortage of evidence on this diagnostic method.

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