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Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Hair transplant surgery is a good cosmetic solution for people with little or no pubic hair, especially to boost their self-esteem.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Pubic hair transplantation can help women with little to no pubic hair, using scalp hair for a natural look and requires careful aftercare.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

The anti-ageing treatment market is growing by exploiting fears of ageing with unproven promises, which could harm public trust and genuine science.

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.

Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.

Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.

Dermatologists should customize cosmetic treatments for dark-skinned patients to minimize risks and complications.

Higher fluoride levels may delay puberty in boys.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

The document concludes that diagnosing PCOS requires a thorough approach, considering various symptoms and risks, and calls for improved methods to identify PCOS types and prevent diabetes.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.

Fractional resurfacing is safe and effective for certain skin conditions in Asian patients, but care must be taken to avoid skin pigmentation issues.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.