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Neuropathic pruritus is a commonly overlooked and wrongly diagnosed type of chronic itching that is hard to treat.

Human skin can make serotonin and melatonin.

Tianeptine, an antidepressant, may prevent stress-induced hair loss in mice.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.

Finasteride reduces movement issues in Parkinson's disease rats.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Using too much minoxidil foam can cause a rare movement disorder with facial twitching, but symptoms go away when the correct dose is used.

Early NAS level changes affect alcohol consumption vulnerability.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.