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Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Father's finasteride use may affect son's fertility and testicular function.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Early hormones shape sex-specific differences in rat glands.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Finasteride helps protect brain in old male rats.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Both estrogens and androgens are important for health in both males and females.