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Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

CDP is crucial for lung and hair follicle cell development.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Cathepsin L is essential for normal hair growth and development.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.