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Hair follicles may soon be used more for targeted and systemic drug delivery.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.

Wounded skin cells can revert to stem cells and help heal.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Understanding how acne develops in different diseases could lead to new treatments.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.

Sebum production varies by individual and is influenced by age, gender, and hormones, affecting skin and hair health.

Sensitive scalp has higher pH, more redness, abnormal sebum, and altered bacterial makeup.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Artificial sebum L closely mimics human sebum for drug delivery research.

Using iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles increases drug release but reduces its targeting to hair follicles.

Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.

Sebum helps protect human skin from microbes.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Nanoparticles show potential for controlled release of hair loss drugs, improving treatment effectiveness.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.

Microsponges delivery system is a safe, versatile method for controlled drug release in various treatments.

Squarticles, tiny particles made from sebum-derived lipids, can effectively deliver minoxidil, a hair growth drug, directly to hair follicles and skin cells, with less skin penetration and more tolerability.

Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.