research Is It Getting in the Hair? Cortisol Concentrations in Native, Regrown, and Segmented Hairs of Cattle and Pigs After Repeated ACTH Administrations
Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.
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research Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research Physical Inactivity Is a Disease Synonymous With a Non-Permissive Brain Disorder
Physical inactivity is a primary cause of many human illnesses.
research Chronic Administration of Minoxidil Protects Elastic Fibers and Stimulates Their Neosynthesis with Improvement of the Aorta Mechanics in Mice
Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
research Ketoconazole Use in the Treatment of Ovarian Hyperandrogenism
Ketoconazole can treat ovarian hyperandrogenism but should be used cautiously with monitoring and birth control.
research Highly Efficient Nucleophilic Addition of Alkyl Grignard Reagents to 17-Ketosteroids in the Presence of Cerium(III) Chloride: Synthesis of 17α-Propyl-17β-Hydroxy-4-Androsten-3-One, an Androgen Receptor Antagonist
Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.
research Within-Person Changes of Cortisol, Dehydroepiandrosterone, Testosterone, Estradiol, and Progesterone in Hair Across Pregnancy, with Comparison to a Non-Pregnant Reference Group
Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.
research The Anxiolytic-Like Effects of Estazolam on a PTSD Animal Model
Estazolam reduces anxiety-like behavior in PTSD by increasing allopregnanolone levels.
research An Update of Hair Shaft Disorders
Advances in genetics may lead to targeted treatments for hair disorders.
research Red Ginseng (Panax Ginseng Meyer) Oil: A Comprehensive Review of Extraction Technologies, Chemical Composition, Health Benefits, Molecular Mechanisms, and Safety
Red ginseng oil is believed to have various health benefits and is safe, but more research is needed to fully understand how it works.
research Hair-Growth Promoting Effect and Anti-Inflammatory Mechanism of Ginkgo Biloba Polysaccharides
Ginkgo biloba polysaccharides may reduce inflammation and promote hair growth in mice with hair loss.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research The Use of Neurotoxins in the Male Face
Men need higher doses of botox than women and a different approach for facial aesthetics due to their unique facial features and muscle mass.
research CD8-Positive Lymphocytes in Graft-Versus-Host Disease of Humanized NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ Mice
CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
research Celery Ameliorating Against Neurobehavioral and Neurochemical Disorders of Perinatal Lipopolysaccharides Exposure in Mice Offspring
Celery helps protect against developmental and brain issues in mice exposed to certain toxins.
research Induced Pluripotent Stem Cell Line MUSIi006-A Derived from Hair Follicle Keratinocytes as a Non-Invasive Somatic Cell Source
Hair samples can be used to create stem cells easily and non-invasively.
research Dermatologic Diseases in Ferrets: Comprehensive Review and Treatment
The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.
research Alopecia Areata: Case Report and Review of Pathophysiology and Treatment with JAK Inhibitors
JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
research Ethnobotany, Phytochemistry, Pharmacology, and Conservation of the Genus Calanthe R. Br. (Orchidaceae)
Calanthe orchids have medicinal potential and contain 265 chemical compounds, but are underexplored.
research Frontal Fibrosing Alopecia: A New Autoimmune Entity?
Frontal Fibrosing Alopecia might be an autoimmune disease.
research Simultaneous LC-MS/MS Quantification of Glucocorticoids, Melatonin, and Its Metabolites in Hair
The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
research A Review on Ethnopharmacology, Phytochemistry, Pharmacology and Potential Uses of Portulaca Oleracea L.
Purslane has many health benefits and potential uses in medicine, food, and farming.
research A Review of the Botany, Ethnopharmacology, Phytochemistry, Pharmacology, Toxicology, and Quality of Anemarrhena Asphodeloides Bunge
The plant Anemarrhena asphodeloides has multiple health benefits but its safety at certain doses is uncertain.
research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis Explaining Paradoxical Results
5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
research Hypertrichosis of the Malar Areas and Poliosis of the Eyelashes Caused by Latanoprost
Latanoprost eye drops caused excessive hair growth and eyelash whitening in a woman.
research The Distribution of Melanocytes and the Degradation of Melanosomes in Fetal Hair Follicles
Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.
research Direct Quantitative Digital Autoradiography Of Testosterone Metabolites In The Pilosebaceous Unit: An Environmentally Advantageous Trace Radioactive Technology
The method accurately measures testosterone metabolites with high sensitivity and low environmental impact.
research Markers of Peripheral Androgen Action In Vivo and In Vitro
Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
research Lupus Erythematosus Tumidus with Autoimmune Thyroid Dysfunction as the First Presentation of Systemic Lupus Erythematosus: A Case Report and Review of the Literature
Recognizing LET and AITD can help diagnose SLE early for better treatment.
research Conceptual Basis for Use of Chemotherapeutic Agents and Their Pharmacology
The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.