December 2024 in “Journal of Cosmetic Dermatology” This study found that exosomes derived from platelet-rich plasma show preclinical promise for wound healing but lack sufficient data for other dermatological uses like hair growth and skin rejuvenation.
September 2024 in “Advanced Biomedical Research” In this study, chick embryo extract enhanced neuronal differentiation and trophic factor expression in rat hair follicle stem cells, suggesting potential improvements for stem cell therapies in neurodegenerative diseases.
July 2024 in “Frontiers in Bioengineering and Biotechnology” In this mouse study, the researchers found that cryopreserving nanofat at -20°C maintained its viability and regenerative potential, comparable to freshly generated nanofat, supporting its potential for repeated use in regenerative applications.
December 2023 in “Regenerative therapy” In this review, the authors reported that exosomal miRNA-based therapies showed promising therapeutic effects on nine skin diseases in animal models, with enhanced outcomes observed when using miRNA-overexpressing exosomes compared to natural ones; however, no comparisons to standard treatments were available.
May 2023 in “International Journal of Molecular Sciences” This review highlights the complications of radiation therapy, specifically radiation cystitis, and explores the potential of mesenchymal stem cell-based therapies for tissue repair while discussing their therapeutic potential and limitations.
February 2022 in “Journal of clinical research and reports” This article discusses the potential uses of plasma therapy for various conditions, including wound healing and Covid-19, but presents no new clinical findings; the authors highlight its increased demand since the Covid-19 outbreak.
5 citations
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July 2025 in “Journal of Clinical Medicine” This study reviewed existing literature on mesotherapy and developed evidence-based guidelines, which support its standardized and safe use for osteoarticular pain, rehabilitation, and dermatology, marking a shift from practice based on personal beliefs to an evidence-based approach.
6 citations
,
February 2021 in “Frontiers in Neurology” This study found that cyclosporine-A might significantly increase the risk of cerebral venous and arterial thrombosis in patients with aplastic anemia.
2 citations
,
August 2022 in “Animals” This review discusses the potential use of essential oils and melatonin as nutraceuticals in dogs, highlighting their promising applications for addressing conditions like stress, anxiety, sleep disorders, and alopecia.
October 2025 in “Journal of Drug Delivery and Therapeutics” In this review, the researchers compared the traditional use of Senna Makki in Unani medicine for various ailments to modern pharmacological evidence, endorsing its role as a laxative but indicating further research is needed for its efficacy in other therapeutic areas.
February 2025 in “Intisari Sains Medis” This article explores the potential mechanisms by which polydeoxyribonucleotide (PDRN) could improve skin quality, slow aging, and enhance skin regeneration, but reports no new clinical findings.
May 2012 in “Research and reports in neonatology” This article presents a case of Klippel-Trénaunay syndrome with limb hypertrophy, port-wine stains, angiokeratoma, and venous varicosities, but reports no new findings beyond this case description.
506 citations
,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.
143 citations
,
April 2018 in “Electronic physician” This article discusses the potential benefits of safflower in traditional Persian medicine for various conditions and highlights the need for comprehensive phytochemical research, without reporting new clinical results.
91 citations
,
July 2004 in “BMJ. British medical journal” This review covers the epidemiology, clinical features, and treatment of four common skin infections in children, reporting no new experimental findings.
58 citations
,
June 2012 in “Journal of Alternative and Complementary Medicine” This review analyzes the traditional Iranian medicine uses of Citrullus colocynthis and compares them with modern phytotherapy findings, reporting no new clinical results but noting safety concerns and dosage considerations.
48 citations
,
July 2001 in “Clinics in Dermatology” Cosmetics enhance beauty, fix defects, and intimidate enemies, with varying cultural standards and alternative methods.
40 citations
,
November 2016 in “Molecules” This review discusses the historical and current use of ribosome-inactivating protein-expressing plants in traditional medicine across various cultures and regions, highlighting their role despite a lack of scientific validation.
July 2024 in “International Journal of Pharmaceutical Sciences and Medicine” This review highlights that Nyctanthes arbor-tristis contains numerous phytochemicals and has traditional uses for various conditions. It also reports pharmacological activities, suggesting potential benefits for diabetes, cancer, inflammation, and more.
January 2024 in “Journal of Pharmacognosy and Phytochemistry” This paper reviewed the medicinal properties and historical Unani uses of Ranunculus sceleratus (Kabīkaj), detailing its identification, uses, and both beneficial and adverse effects, while noting its current lack of use due to availability and identification challenges.
October 2022 in “Journal of Pharmaceutical Negative Results” This review examines the therapeutic effects of photobiomodulation on severe medical illnesses but reports no new clinical results; it emphasizes its potential in neurology, pulmonology, inflammation, dermatology, wound healing, and oncology.
July 2022 in “Journal of bio innovation” This article discusses the role of Panchakarma, a set of five Ayurvedic therapies, in detoxifying the body, as described in traditional Ayurvedic texts.
January 2019 in “Advances in Environmental Biology” This article discusses the structure and function of sebaceous glands and their role in skin moisture but reports no new research findings.
November 2008 in “Journal of Generic Medicines” The document updates on EU legal changes, including pharmaceutical patents, class actions in Italy, and various drug-related rulings.
8 citations
,
October 2013 in “The Journal of Spinal Cord Medicine” In this study, fungal infections and seborrheic dermatitis were identified as the most common skin conditions among spinal cord injury patients referred to dermatology, impacting quality of life.
227 citations
,
February 1989 in “The Journal of Comparative Neurology” This study found that calcitonin‐gene‐related peptide immunoreactive sensory axons in rats are predominantly involved in tissue maintenance rather than nociceptive functions.
19 citations
,
November 2014 in “Journal of Comparative Physiology A” This study found that Cupiennius salei spiders have specialized mechanosensitive hairs on their legs that adaptively respond to joint movements during walking, suggesting a proprioceptive function.
March 2005 in “Journal of The American Academy of Dermatology” Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.
3 citations
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December 2023 in “Pain Medicine” This case report described how peripheral nerve stimulation provided significant pain relief and reversal of dermatological symptoms for a female patient with complex regional pain syndrome after conventional treatments failed.
50 citations
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April 2021 in “Frontiers in Immunology” This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.