September 2022 in “Journal of pharmaceutical sciences” This study found that adding hydroxypropyl cellulose to minoxidil formulations significantly increased scalp retention and penetration compared to other formulations, potentially leading to reduced application frequency and improved efficacy.
5 citations
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May 2021 in “International Journal of Cosmetic Science” This review discusses the evidence for a cause-and-effect relationship between scalp condition and hair condition, and reports no new clinical results from trials.
40 citations
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January 2018 in “International journal of trichology” This article reviews the relationship between scalp conditions and hair health, suggesting that shampoos with Malassezia inhibitory agents may help reduce premature hair loss, but it presents no new clinical results.
53 citations
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June 1982 in “The BMJ” Cooling the scalp below 22°C before and during chemotherapy can help prevent hair loss.
1 citations
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August 2021 in “International journal of cosmetic science (Print)” This study reported that using piroctone olamine in either a shampoo or leave-on product form significantly increased hair retention and improved scalp condition in women with perceived hair thinning.
This study found that scalp cooling effectively prevented visible hair loss in over half of patients undergoing highly alopecia-inducing chemotherapy, yet cognitive appraisal of the treatment had a more significant impact on quality of life than the actual degree of hair retention.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that hair treated with a supplemental hair care product showed significantly higher absorption, deeper penetration, and reduced dryness compared to untreated and water-treated hair, as measured with 3D Raman spectroscopy.
November 2019 in “Quality in primary care” This paper describes Scalp Micropigmentation (SMP) as a cosmetic procedure that creates the appearance of hair through medical hairline tattoos, providing a non-surgical alternative to hair transplants with no downtime.
3 citations
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July 2010 in “Archives of internal medicine” A woman kept her eyelashes during chemotherapy possibly because of her glaucoma eye drops.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This research describes how herbal hair serums, containing natural components like pomegranate peel and aloe vera, can support hair health by nourishing the scalp, stimulating follicles, and enhancing hair strength and shine, aligning with growing interest in herbal and chemical-free personal care products.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study reviews the benefits of herbal hair serums, highlighting their antioxidant and anti-inflammatory properties from natural ingredients like pomegranate peel and aloe vera, which nourish the scalp and promote healthy hair growth while improving hair strength and texture.
November 2025 in “Journal of Ayurveda and Integrated Medical Sciences” This study evaluated an herbal hair dye made from plant-based ingredients, finding it stable, non-toxic, and effective in providing lasting color, improving hair texture, and reducing hair fall, making it a viable and eco-friendly alternative to chemical dyes.
This study found that nanoparticles developed with minoxidil-loaded thiolated β-cyclodextrins showed improved drug retention on hair surfaces and did not cause skin irritation in rabbits, suggesting potential for topical scalp disease treatment.
January 2023 in “Revista Eletrônica Acervo Saúde” This integrative literature review found that oral Minoxidil is a favorable alternative for individuals intolerant to topical application, effectively treating various forms of alopecia, though side effects like increased hair growth and minor dermatological reactions are noted.
14 citations
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January 2019 in “Annals of plastic surgery” This case report details a face and scalp transplant in a patient with granulomatosis with polyangiitis and trauma, showing an encouraging 3-year outcome without disease relapse or severe complications.
131 citations
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October 2004 in “Clinical Cancer Research” This study suggests that applying topical Tempol to the scalp before whole brain radiation may protect against radiation-induced alopecia and is safe and well-tolerated.
June 2025 in “Cancer Management and Research” This study found that scalp cooling resulted in visible hair retention in 53% of breast cancer patients undergoing Epirubicin/Cyclophosphamide and Paclitaxel treatment, with factors like hair bulb diameter, shaft diameter, and anagen rate significantly predicting outcomes.
November 2017 in “Expert review of quality of life in cancer care” This review observed that recent trials in the United States reported scalp cooling devices being effective and well tolerated for many patients in preventing chemotherapy-induced alopecia, with hair retention rates varying based on specific chemotherapy drugs and regimens.
January 2026 in “Anti-Infective Agents” This study developed a nanohydrogel containing itraconazole and mometasone for treating scalp and beard fungal infections, demonstrating improved antifungal efficacy, longer retention, and better patient acceptance compared to conventional treatments.
29 citations
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September 2014 in “American Journal of Dermatopathology” This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.
December 2025 in “Frontiers in Medicine” This study assessed patient satisfaction and hair retention in 15 individuals with alopecia treated with Biofibre ® 4.0 artificial hair implants, finding high levels of satisfaction and excellent biocompatibility, with no significant adverse reactions reported after one year.
1 citations
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May 2007 in “International Journal of Dermatology” Minoxidil, when applied to the scalp, can stimulate hair growth but effects vary, stop if treatment ends, and it may cause side effects like fluid retention.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review concludes that herbal nanoemulgel-based hair dyes, incorporating natural ingredients, enhance dye penetration and retention while providing additional hair and scalp health benefits compared to conventional dyes, though further studies are needed to confirm long-term safety and efficacy.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that herbal nanoemulgel-based hair dyes, enriched with natural ingredients, improve dye penetration and retention and offer additional hair and scalp benefits compared to conventional dyes, although further research is necessary to verify their safety and efficacy for long-term use.
November 2024 in “International Journal of Cosmetic Science” This study demonstrated that several botanical extracts possess antioxidant properties, reducing oxidative stress and lipid oxidation in scalp treatments, with rosemary extract showing potential to improve scalp condition in a 4-week consumer trial.
This study evaluated various herbal blends of powdered leaves, including Henna and Indigo, for their coloring and sensitivity reactions, finding Henna and Indigo to be effective natural colorants for achieving a reddish-brown hair color with better retention than marketed herbal hair dyes.
December 2023 in “Pharmaceutics” In this study, nanoparticles developed with Minoxidil-loaded thiolated β-CDs showed promise for topical scalp use, as they significantly improved drug retention on hair and displayed no irritation in rabbits.
November 2023 in “Computational and Structural Biotechnology Journal” This study reports the development of a prototype robotic hair transplant system capable of efficiently harvesting and implanting hair grafts, showing promising accuracy and performance in tests using a spherical scalp phantom.
July 2007 in “Clinical Risk” A woman got severe scalp burns from a salon's improper hair bleaching treatment.
13 citations
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June 2016 in “Dermatologic Therapy” This study found that minoxidil applied to a damp scalp may increase drug penetration in vitro, potentially improving treatment effectiveness.