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Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

Fractional photothermolysis helps wounds heal with minimal scarring.

BRG1 is essential for skin cells to move and heal wounds properly.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Different types of skin cells play specific roles in development, healing, and cancer.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.

Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.

Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.

Researchers developed a mouse model that tracks hair growth using bioluminescence, improving accuracy in studying hair cycles.