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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Myrtle has various health benefits and potential for medicine development.

Hair follicles may soon be used more for targeted and systemic drug delivery.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.