Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that overexpression of Hoxc13 in GC13 mouse models affects hair follicle differentiation by interacting with medulla-specific genes, particularly Foxq1, suggesting a regulatory pathway for medulla differentiation.

This case report describes improvement in amenorrhea, alopecia, and muscle spasms in a 13-year-old girl with Satoyoshi syndrome following treatment with daily tacrolimus and alternate-day oral prednisolone.

This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.

The researchers reported that miR-21 expression increases with age in both human and mouse skin and may contribute to skin aging by targeting the chromatin remodeler SATB1 in keratinocytes.

This study developed a pharmacokinetic/pharmacodynamic model for finasteride, concluding that finasteride's nonlinear pharmacokinetics are likely due to its saturable binding to 5alphaR2.

In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.

This study found that both patients and physicians expressed dissatisfaction with disease control in systemic lupus erythematosus, with patients showing greater dissatisfaction than physicians regarding symptoms.

This case report describes a 9-year-old Thai girl with Satoyoshi syndrome, where oral corticosteroid therapy significantly improved her painful muscle spasms and alopecia.

This study found that human hair fibers significantly improve the shear behavior of dry sand, but under saturated conditions, the reinforcement sustains shear strength similar to unreinforced sand.

This review of 64 published cases of Satoyoshi syndrome from 1967 to 2018 reports that corticosteroids were the most widely used and effective treatment, improving symptoms in most cases, while muscle relaxants like dantrolene primarily benefited muscle symptoms without affecting other symptoms.

This paper reviews Satoyoshi syndrome and suggests diagnostic criteria to differentiate its subtypes, emphasizing the importance of testing alopecia areata patients for antinuclear antibodies, muscle spasms, and diarrhea.

This report documents the first adult onset case of Satoyoshi syndrome in South America, highlighting possible improvement with immunosuppressive treatment using corticosteroids and azathioprine.

This study reports that improvement with corticosteroids or other immunosuppressants in Satoyoshi syndrome suggests an autoimmune origin, supported by its association with other autoimmune diseases and autoantibodies.

This article shares a case of Satoyoshi syndrome that was misdiagnosed as vitamin D-dependent rickets for several years.

This case report describes a rare instance of Satoyoshi syndrome in a 27-year-old Asian American woman, notable for her normal ovarian function despite typical syndrome features.

In this case report, researchers highlight a 57-year-old HIV patient on ritonavir who developed Cushing’s syndrome from over-the-counter intranasal fluticasone, underscoring the risks of drug interactions and the importance of counseling patients about potential steroid ingredients in OTC products.

In this study, researchers found that transgender men exhibited impaired autonomic modulation during sympathetic stimulation compared to cisgender women, potentially due to testosterone treatment affecting cardiac autonomic modulation.

This case report details a patient with Satoyoshi syndrome presenting with uveitis and impending central retinal vein occlusion, a previously undocumented complication, suggesting uveitis as a potential complication of the syndrome.

This case report illustrates a rare instance of mixed germ cell tumor in the pituitary with hyperandrogenism, emphasizing the importance of thorough examination and hormone evaluation in identifying hormonal dysfunctions.

In this case report, an 80-year-old woman experienced elevated alkaline phosphatase levels due to the use of Viviscal hair supplements. Her levels returned to normal after discontinuing the supplement, highlighting the need for clinicians to consider supplements as potential causes of abnormal lab results.

This case report documented the management of a 46-year-old female with Marine-Lenhart syndrome, combining antithyroids with minimally invasive sclerotherapy to achieve euthyroidism and reduce thyroid nodule size by 58%.

This case study reported a unique instance of a benign adrenal adenoma co-secreting cortisol and DHEA-S, which initially mimicked PCOS symptoms. Surgical removal resulted in significant clinical improvement, confirming the diagnosis of cyclic adrenal Cushing's syndrome.

This report highlights that Klinefelter syndrome is often underdiagnosed due to phenotypic variability and emphasizes the importance of thorough physical examinations to improve diagnostic timing.

This study observed that finasteride, while lowering cholesterol levels, did not decrease the prevalence of clinical cardiovascular events or new ECG abnormalities in men with benign prostatic hyperplasia compared to controls, suggesting a potential disconnect between cholesterol management and cardiovascular risk reduction with this treatment.

In this case study, a 69-year-old woman with severe hypercortisolism developed acute adrenal insufficiency after starting ketoconazole treatment, highlighting the need for cautious dosing and close monitoring of adrenal function, particularly in patients with prior glucocorticoid exposure.

The researchers reported that individuals with non-alcoholic fatty liver disease and nutritional deficiency often exhibit iron and estrogen deficiencies, which may contribute to liver cell stress and fibrosis.

This case report highlights that macro-TSH, a rare condition causing falsely elevated TSH despite normal thyroid hormone levels, can lead to misdiagnosis and unnecessary treatment; identifying TSH antibodies and fractionation chromatography can prevent incorrect management, as demonstrated in a 19-year-old patient.

This case report describes a 45-year-old woman with recurrent cyclic Cushing’s disease whose symptoms improved with metyrapone and hydrocortisone treatment.

This case report details an atypical presentation of Hodgkin's lymphoma in an 87-year-old man, where severe hypercalcemia and mental status changes prompted further investigation and diagnosis.

In this case report, successful management of a pituitary macroadenoma was achieved with thyroid hormone therapy, leading to reduced tumor size and improvement in symptoms like galactorrhea and headaches.