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Most children with skin inflammation taking methotrexate had lab abnormalities, but liver issues often improved without changing the medication dose.

A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.

Copper treatments increase copper in all tissues, but brindled female mice accumulate much more copper in their kidneys without clinical effects, unlike brindled male mice where brain copper deficiency is clinically significant.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

A woman with a skin disorder was found to have hepatitis C, which may be linked, and was safely treated with methotrexate.

PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.

The research found that certain microRNAs are important for human hair growth and health.

Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

The endocannabinoid system affects oil production and inflammation in skin cells.

Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.

Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.

Blocking Prostaglandin D₂ (PGD₂) could help treat hair loss.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.

A 37-year-old man with hair loss and skin issues was successfully treated with oral antibiotics, highlighting the need for early treatment. Long-term care includes low-dose antibiotics and avoiding caps and wigs.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.