August 2018 in “Journal of The American Academy of Dermatology” Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.
102 citations,
July 2007 in “Genes & Development” A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.
38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
30 citations,
January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
125 citations,
September 2019 in “Journal of Clinical Immunology” Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
91 citations,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
74 citations,
September 2006 in “Cell Cycle” The HR protein's role as a repressor is essential for controlling hair growth.
7 citations,
August 2020 in “Animal biotechnology” A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.
6 citations,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
62 citations,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
29 citations,
January 2014 in “Frontiers in physiology” Understanding and tracking our body's natural daily rhythms could help improve heart health.
15 citations,
January 2014 in “Dermatology” Some patients treated with peginterferon and ribavirin for chronic hepatitis C had mild to moderate skin reactions, but treatment did not need to be stopped.
14 citations,
March 2007 in “Pediatric pulmonology” Inhaled steroids in children may cause excessive hair growth and not always go away after stopping the medication.
5 citations,
September 2022 in “Research Square (Research Square)” CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
August 2018 in “Journal of The American Academy of Dermatology” The conclusion is that finasteride is linked to an increased risk of suicidal thoughts and a higher risk of completed suicide when used for hair loss.
260 citations,
June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
222 citations,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
39 citations,
January 2012 in “International Journal of Trichology” Melatonin solution helps treat hair loss in men and women.
17 citations,
June 2019 in “BMC genomics” Non-coding RNAs help control hair growth in cashmere goats.
7 citations,
December 2017 in “Journal of the European Academy of Dermatology and Venereology” Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
4 citations,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
January 2024 in “Diabetes & metabolism journal” Disrupting natural body clocks increases the risk of developing type 2 diabetes.
January 2012 in “Else Kröner-Fresenius Symposia” Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
February 2008 in “Experimental dermatology” Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
11 citations,
June 2021 in “Frontiers in Cell and Developmental Biology” Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
January 2023 in “Annals of dermatology/Annals of Dermatology” A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.
318 citations,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
5 citations,
January 2023 in “International Journal of Molecular Sciences” Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
November 2021 in “Evidencia” Young patients using finasteride may have higher risks of anxiety, depression, and suicidal thoughts.