13 citations,
June 2020 in “BMC genomics” A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
10 citations,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
6 citations,
May 2022 in “Frontiers in physiology” Injecting CHIR-99021 into goose embryos improves feather growth by changing gene activity and energy processes.
4 citations,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
1 citations,
November 2018 in “Therapeutic Delivery” New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
January 2024 in “Burns and trauma” The skin microbiome helps heal wounds and can be targeted to improve healing.
451 citations,
March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
341 citations,
November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
97 citations,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
75 citations,
November 2016 in “Medicines” Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.
48 citations,
July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
45 citations,
October 2014 in “Stem cell research & therapy” Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.
16 citations,
July 2019 in “Journal of Cellular Biochemistry” Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.
14 citations,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
10 citations,
January 2016 in “Elsevier eBooks” Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
8 citations,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
3 citations,
January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.
2 citations,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
1 citations,
July 2020 in “Dermatology” Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.
New insights into cell communication in psoriasis suggest innovative drug treatments.
17 citations,
May 2014 in “Cell transplantation” Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
13 citations,
April 2019 in “International journal of molecular sciences” Acyzol could help treat conditions caused by zinc deficiency.
375 citations,
June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
22 citations,
April 2012 in “The American journal of pathology” Loss of Msx2 function causes eye development issues similar to Peters anomaly.
4 citations,
October 2021 in “Journal of Cellular and Molecular Medicine” White blood cells and their traps can slow down the process of new hair growth after a wound.
2 citations,
January 2023 in “Frontiers in Genetics” Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
1 citations,
April 2023 in “International journal of molecular sciences” Certain skin proteins can form anchoring structures without the protein AMACO.