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Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Valproic acid may help hair grow and could be a safe treatment for hair loss.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

A man's gray hair got darker and thicker after using a psoriasis drug.

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

The document concludes that more research is needed to create specific drugs for treating male pattern baldness.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

Topical tretinoin effectively treated sebaceous filaments, improving skin appearance.

Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.

Topical bexarotene 1% gel might help regrow hair in alopecia areata and is generally safe.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.

The ketogenic diet might improve certain skin conditions, but more research is needed to confirm its effectiveness.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.

Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.

Claudin expression changes help the skin respond to injury.

Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.

CRABP2 helps increase the growth of cells important for hair growth by activating a specific growth pathway.

Nanocarriers with plant extracts show promise for safe and effective hair growth treatment.