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This study reports that the novel small molecule IM176OUT05, by modifying stem cell metabolism, promoted hair regrowth and increased hair follicle numbers in mice.

The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.

In this phase 2a study of adults with alopecia areata, researchers observed that ritlecitinib treatment did not result in significant differences in brainstem auditory evoked potential changes or axonal swelling compared to placebo, suggesting the dog toxicity findings may not be clinically relevant in humans.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.

This article reviews the stages and regulation of the hair cycle, highlighting molecular regulators involved, but it does not present new research findings.

This article discusses the treatment of androgenetic alopecia and alopecia areata with finasteride and minoxidil but reports no new clinical results.

This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.

This review summarizes the major events and regulators of the hair cycle in mammals but reports no new experimental results; it emphasizes the complex regulation of stem cell activation and differentiation during hair growth.

This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.

The study reports that Fgf18 and Tgf-β2 signaling pathways in hair follicle stem cells have opposing effects on the timing of hair cycle transitions, influencing the shift from telogen to anagen phases.

In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.

This study found that cyclosporin A treatment enhances hair growth in mice by inhibiting calcineurin-NFAT1 activity, which alters keratinocyte differentiation and apoptosis-related gene expression in hair follicles.

This study found that IGF-1 injections increased hair follicle number and growth phase duration in wild-type mice, suggesting potential for baldness treatment.

This study found that thrombospondin-1 plays a critical role in hair follicle cycle regulation, with deficiency prolonging follicle growth and overexpression delaying it through antiangiogenic effects.

This study observed that Aconiti Ciliare Tuber extract may promote hair growth in mice by activating the Wnt/β-catenin signaling pathway.

This study found that minor ginseng saponin F2 may promote hair growth more effectively than finasteride by enhancing anagen induction and modulating the Wnt signaling pathway in cell and mouse models.

This study revealed that deficiency in the enzyme FA2H in mice affected sebaceous gland function, altered sebum composition, and caused cycling alopecia, highlighting FA2H's role in hair follicle homeostasis.

This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.

In this study, researchers developed a non-invasive method to distinguish exogen hair from telogen hair on the human scalp, finding that normal exogen hair levels are generally less than seven hairs per cm².

This article reviews common causes of hair loss, noting that a well-directed history and examination are often sufficient for diagnosis, and reports no new clinical findings.

This study found that L-type channel blockers can induce hair growth in Timothy syndrome by overcoming delays in anagen phase, suggesting a potential therapeutic role for tissue regeneration.

This review outlines a systematic method for diagnosing hair loss and presents no new findings; the authors emphasize the importance of biopsy in cicatricial alopecia cases.

This review explores the autoimmune hypothesis of alopecia areata and the possible genetic and melanogenesis-associated autoantigens, but reports no new clinical findings.

In this study, topical application of Hominis Placenta significantly promoted hair regrowth and increased hair density in C57BL/6 mice, suggesting its potential as a treatment for alopecia.

In this study, an ethanol extract of Crinum asiaticum was observed to significantly increase hair-fiber lengths and promote hair growth in rat vibrissa follicles and C57BL/6 mice.

This study found that 15-dPGJ2 promotes apoptosis in human follicular keratinocytes, suggesting its potential role in developing hair loss prevention treatments through DP2 antagonism.

In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.

This study found that Sox10 may play a role in early hair follicle development and cycling, as it is expressed in specific regions of the hair follicle during different phases of the hair cycle in mice.

In this animal study, the researchers found that Schisandra nigra extract may promote hair growth by extending the anagen phase and reducing TGF-beta2 expression.