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This study highlights that while there are no FDA- or ANVISA-approved treatments for children with alopecia areata, JAK inhibitors are emerging as a promising therapeutic option for this population.

In this case report, the authors describe a child with treatment-resistant alopecia areata who successfully responded to leflunomide and anthralin, proposing this combination as a potentially cost-effective alternative for managing recalcitrant cases by possibly inhibiting the JAK/STAT pathway.

This study found that Chinese female patients with systemic autoimmune diseases treated intravenously with cyclophosphamide were more likely to experience gastrointestinal discomfort, myelosuppression, and alopecia.

This study found that 5% topical minoxidil solution led to better hair regrowth response and quality in severe alopecia areata compared to 1% solution, despite regrowth often being cosmetically unacceptable.

This study found that sterile fucoidan promotes T cell proliferation but reduces differentiation at higher concentrations and suppresses osteogenic differentiation in co-cultured environments.

This study reports that persistent chemotherapy-induced alopecia in breast cancer patients frequently resembles androgenetic alopecia, and treatment with minoxidil, alone or with antiandrogens, improved hair density in many cases.

Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.

This article reviews the characteristics and distribution of alopecia areata and reports no new clinical results.

In this study, 12 months of cyproterone acetate and ethinyl oestradiol treatment significantly reduced hair growth rate and certain hormone levels in hirsute women, though hair density and prolactin levels remained unchanged.

ChatGPT can be a helpful dermatology resource but should not replace professional consultations.

This study found that overexpression of sPLA2-IIA in homozygous mice resulted in cyclic alopecia, a halt in hair follicle cycling, and impaired wound healing due to complete loss of hair follicle stem cells.

This study found that laser Doppler velocimetry can non-invasively predict topical minoxidil response by correlating scalp blood flow changes with sulfotransferase enzyme activity in women with pattern hair loss.

This review discusses recent advances in the understanding of alopecia areata, focusing on immunity and genetics, and presents potential targets for therapy without reporting new clinical results.

In this study, researchers observed that acute stress increased levels of the enzyme 5αR2 in the medial prefrontal cortex of male rats, affecting stress reactivity, but this effect was not seen in females.

This study found that modeling and simulation effectively informed decision-making and dose selection for ritlecitinib in treating alopecia areata, supporting an accelerated drug development strategy.

In this study, researchers identified significant differences in protein expression patterns in scalps affected by central centrifugal cicatricial alopecia, notably upregulation of immune pathways and fibrosis markers and downregulation of metabolic proteins, suggesting unique disease mechanisms and potential therapeutic targets.

In this study, fMRI results suggested that mechanical stimulation evoked a stronger prickle sensation comprising both pain and itch on hairy skin compared to glabrous skin.

This case report identifies a novel maternally inherited MBTPS2 variant associated with an expanded phenotypic spectrum of BRESHECK syndrome, including cytopenias, bone marrow fibrosis, and chronic diarrhea.

This case report documented successful full hair regrowth in an 8-year-old with alopecia universalis after oral tofacitinib treatment, but mild headaches led to discontinuation.

This study indicates that individuals exposed to PPD mount varying immune responses, with either tolerance, subclinical inflammation, or allergy, suggesting no true non-responders to PPD.

This study found that a 15% topical minoxidil solution improved hair regrowth in 60% of women with female pattern hair loss who did not respond to the standard 5% solution, without adverse effects.

This study reviewed the dosages of products approved in Japan from 2003-2010 and found that 28.1% were at different levels than in the U.S., with limited evidence suggesting different clinical responses.

This study demonstrated that FOXO3 influences feather follicle development in goose embryos by regulating the Wnt/β-catenin signaling pathway in dermal fibroblasts, resulting in changes to feather size and structure without altering follicle density.

Over 45% of patients with alopecia areata benefit from ritlecitinib, mostly within a year.

This study found that Arc/Arg3.1 expression in hippocampal neurons is regulated by sex steroids in a sex-dependent manner, with E2 increasing expression in females and DHT in males.

PRP treatment helps 70.1% of hair loss patients after two sessions.

In this study, the authors identified the DHRS9 SNP rs72623193 as most significantly associated with response to dutasteride in treating male pattern hair loss, with additional variants potentially contributing.

In this study, 70 patients with alopecia areata who received intralesional triamcinolone showed a significant reduction in black dots, yellow dots, broken hair, and tapering hair, while achieving a 60% success rate in hair regrowth.

This study found PRP treatment significantly increased hair count and anagen hairs in male patients with androgenetic alopecia, but there was no correlation between therapeutic response and platelet or growth factor levels.